ArticleJournal of neurology, neurosurgery, and psychiatry2005
Intravascular lymphoma: magnetic resonance imaging correlates of disease dynamics within the central nervous system.
Article in Journal of neurology, neurosurgery, and psychiatry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 93 citations in OpenAlex.
- Pediatric hemophagocytic lymphohistiocytosis with predominant CNS involvement: MRI features and differential diagnosis.BMC pediatrics · 2026Article
- Lymphoproliferative Disorders Mimicking Rheumatologic Disease: A Clinical Reasoning Perspective.Current allergy and asthma reports · 2025Review
- Article
- Clinical manifestations and outcomes of patients with intravascular large B-cell lymphoma with neurological involvement: highlighting longitudinally extensive myelopathy as a distinct feature.BMJ neurology open · 2025Article
- Review
- Intravascular Lymphoma as a Cause of Recurrent Strokes - Case Report and Review of the Literature.The Neurohospitalist · 2023Article
- A case of intravascular lymphoma presenting with a lesion in the splenium of the corpus callosum.Radiology case reports · 2023Article
- Article
- Imaging of Lymphomas Involving the CNS: An Update-Review of the Full Spectrum of Disease with an Emphasis on the World Health Organization Classifications of CNS Tumors 2021 and Hematolymphoid Tumors 2022.AJNR. American journal of neuroradiology · 2023Review
- Rare central nervous system lymphomas.British journal of haematology · 2022Review
- Current progress and future perspectives of research on intravascular large B-cell lymphoma.Cancer science · 2021Review
- Intravascular lymphoma of the central nervous system: a rare subtype of a common disease.Arquivos de neuro-psiquiatria · 2021Article
- Different imaging patterns of PCNSL and IVL: a case report.BMC neurology · 2019Article
- Disappearing Leukoencephalopathy : A Case of Relapsing-Remitting Intravascular Large B‑Cell Lymphoma with Transient Spontaneous Radiographic Regression.Clinical neuroradiology · 2018Article
- Intravascular large B-cell lymphoma presenting clinically as rapidly progressive dementia.Irish journal of medical science · 2018Review
- Intravascular Lymphoma with an Acute Course of Cerebellar Hemorrhage: A Case Report.Neurologia medico-chirurgica · 2018Article
- Persistent lesion hyperintensity on brain diffusion-weighted MRI is an early sign of intravascular lymphoma.BMJ case reports · 2017Article
- Unusual Magnetic Resonance Imaging and Catheter Angiographic Signs of Intravascular Lymphoma.Clinical neuroradiology · 2015Article
- Neuroimaging of rapidly progressive dementias, part 2: prion, inflammatory, neoplastic, and other etiologies.AJNR. American journal of neuroradiology · 2014Review
- Intravascular lymphomatosis mimicking primary central nervous system lymphoma: a case report and literature review.Case reports in neurology · 2014Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntravascular lymphoma (IVL) is a rare non-Hodgkin's lymphoma with relative predilection for the central nervous system. In the absence of extraneural manifestations, the disease is not recognised until autopsy in the majority of cases underlining the need for new clinical markers.
methodsThis is a retrospective series of five patients with IVL seen at a single institution over three years. An advanced magnetic resonance imaging (MRI) protocol was performed at various time points prior to diagnosis and during treatment.
resultsMRI revealed multiple lesions scattered throughout the cerebral hemispheres; the brainstem, cerebellum, and spinal cord were less frequently involved. On initial presentation, hyperintense lesions were seen on diffusion weighted images suggestive of ischaemia in three of four patients in whom the images were obtained at that time point. In four patients lesions were also identifiable as hyperintense areas on fluid attenuated inversion recovery (FLAIR) sequences. Initial contrast enhancement was encountered in three cases. Diffusion weighted imaging lesions either vanished or followed the typical pattern of an ischaemic small vessel stroke with evolution of abnormal FLAIR signal followed by enhancement with gadolinium in the subacute stage and tissue loss in the chronic stage. Diffusion weighted imaging and FLAIR abnormalities proved to be partially reversible, correlating with the response to chemotherapy.
conclusionWe provide the first detailed description of the dynamic pattern of diffusion weighted MRI in IVL. These patterns in combination with systemic findings may facilitate early diagnosis and serve as a new tool to monitor treatment response.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.