Evidence map›Paper›PMID 15774029›Full record

ArticleGenome biology2005

Comparative context analysis of codon pairs on an ORFeome scale.

Gabriela Moura, Miguel Pinheiro, Raquel Silva, Isabel Miranda, Vera Afreixo, Gaspar Dias, Adelaide Freitas, José L Oliveira, Manuel A S Santos

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Genome biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Codon usage bias.Molecular biology reports · 2022
    Review
  8. Article
  9. The Use of the Rare TTA Codon inIndian journal of microbiology · 2021
    Article
  10. Article
  11. Review
  12. NipahVR: a resource of multi-targeted putative therapeutics and epitopes for the Nipah virus.Database : the journal of biological databases and curation · 2020
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. The Yin and Yang of codon usage.Human molecular genetics · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gabriela MouraCentre for Cell Biology, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal. gmoura@bio.ua.pt
Miguel Pinheiro
Raquel Silva
Isabel Miranda
Vera Afreixo
Gaspar Dias
Adelaide Freitas
José L Oliveira
Manuel A S Santos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Codon context is an important feature of gene primary structure that modulates mRNA decoding accuracy. We have developed an analytical software package and a graphical interface for comparative codon context analysis of all the open reading frames in a genome (the ORFeome). Using the complete ORFeome sequences of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans and Escherichia coli, we show that this methodology permits large-scale codon context comparisons and provides new insight on the rules that govern the evolution of codon-pair context.

Indexed as

CodonCandida albicansCluster AnalysisComputational BiologyEscherichia coliEvolution, MolecularGenomicsOpen Reading FramesRNA, MessengerSaccharomyces cerevisiaeSchizosaccharomycesSoftwareCodonRNA, Messenger

Identifiers

PMID15774029
PMCPMC1088947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.