Evidence map›Paper›PMID 15767702›Full record

ReviewMolecular biotechnology2005

Multilocus sequence typing: Data analysis in clinical microbiology and public health.

Christopher B Sullivan, Matthew A Diggle, Stuart C Clarke

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Development of a multilocus sequence typing tool forJournal of clinical microbiology · 2026
    Article
  2. Article
  3. Article
  4. FromACS omega · 2023
    Review
  5. Prevalence and contamination patterns ofFrontiers in microbiology · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Molecular typing of cytotoxin-producingNew microbes and new infections · 2019
    Article
  10. Microbial sequence typing in the genomic era.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018
    Review
  11. Diversity analysis ofFood science and biotechnology · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Recombination Is a Major Driving Force of Genetic Diversity in the AnaplasmataceaeFrontiers in cellular and infection microbiology · 2016
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher B SullivanScottish Meningococcus and Pneumococcus Reference Laboratory North Glasgow University Hospital NHS Trust, Glasgow, UK.
Matthew A Diggle
Stuart C Clarke

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous computer-based statistical packages have been developed in recent years and it has become easier to analyze nucleotide sequence data and gather subsequent information that would not normally be available. Multilocus sequence typing (MLST) is used for characterizing isolates of bacterial and fungal species and uses nucleotide sequences of internal fragments of housekeeping genes. This method is finding a place in clinical microbiology and public health by providing data for epidemiological surveillance and development of vaccine policy. It adds greatly to our knowledge of the genetic variation that can occur within a species and has therefore been used for studies of population biology. Analysis requires the detailed interpretation of nucleotide sequence data obtained from housekeeping and nonhousekeeping genes. This is due to the amount of data generated from nucleotide sequencing and the information generated from an array of analytical tools improves our understanding of bacterial pathogens. This can benefit public health interventions and the development of enhanced therapies and vaccines. This review concentrates on the analytical tools used in MLST and their use in the clinical microbiology and public health fields.

Indexed as

Bacterial Typing TechniquesMycological Typing TechniquesBacteriaDNA, BacterialDNA, FungalDNA, IntergenicFungiQuantitative Trait LociSequence Analysis, DNADNA, BacterialDNA, FungalDNA, Intergenic

Identifiers

PMID15767702

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.