Evidence map›Paper›PMID 15765130›Full record

ReviewThe Journal of clinical investigation2005

Learning from failure: congestive heart failure in the postgenomic age.

Ivor J Benjamin, Michael D Schneider

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Heart failure: advances through genomics.Nature reviews. Genetics · 2011
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Abnormal calcium "sparks" in cardiomyocytes of post-myocardial infarction heart.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2008
    Article
  16. Uncoupling proteins in heart failure.Current heart failure reports · 2008
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ivor J BenjaminDivision of Cardiology, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA. ivor.benjamin@hsc.utah.edu
Michael D Schneider
Baylor College of Medicine · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis of heart failure is worse than that of most cancers, but new therapeutic interventions using stem and other cell-based therapies are succeeding in the fight against it, and old drugs, with new twists, are making a comeback. Genetically engineered animal models are driving insights into the molecular mechanisms that cause hearts to fail, accelerating drug discoveries, and inspiring cell-based therapeutic interventions for both acquired and inheritable cardiac diseases.

Indexed as

GenomicsHeart FailureAnimalsAnimals, Genetically ModifiedApoptosisCalciumGenetic TherapyHumansMitochondriaNitric OxideOxidative StressProtein KinasesSignal TransductionTranscription, GeneticCalciumNitric OxideProtein Kinases

Identifiers

PMID15765130
PMCPMC1052014
OpenAlexW2053249961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.