ArticleThe Biochemical journal2005
Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.
Article in The Biochemical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
- Systems mapping of bidirectional endosomal transport through the crowded cell.Current biology : CB · 2024Article
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- Cytoskeletal regulation guides neuronal trafficking to effectively supply the synapse.Current biology : CB · 2021Review
- WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System.Endocrinology and metabolism (Seoul, Korea) · 2020Review
- Phosphorylation sites of microtubule-associated protein 1B (MAP 1B) are involved in axon growth and regeneration.Molecular brain · 2019Article
- Reduction of acute mild stress corticosterone response and changes in stress-responsive gene expression in male Balb/c mice after repeated administration of aFood science & nutrition · 2019Article
- Gene Profiling of Nucleus Basalis Tau Containing Neurons in Chronic Traumatic Encephalopathy: A Chronic Effects of Neurotrauma Consortium Study.Journal of neurotrauma · 2018Article
- The calcium-binding protein ALG-2 regulates protein secretion and trafficking via interactions with MISSL and MAP1B proteins.The Journal of biological chemistry · 2017Article
- MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells.The EMBO journal · 2013Article
- LIS1 and DCX: Implications for Brain Development and Human Disease in Relation to Microtubules.Scientifica · 2013Review
- The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini.Neuron · 2012Article
- The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system.Neural regeneration research · 2012Review
- Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function.Journal of cell science · 2011Article
- Polarity regulation in migrating neurons in the cortex.Molecular neurobiology · 2009Review
- Role of MAP1B in axonal retrograde transport of mitochondria.The Biochemical journal · 2006Article
- Lissencephaly 1 linking to multiple diseases: mental retardation, neurodegeneration, schizophrenia, male sterility, and more.Neuromolecular medicine · 2006Review
- The MAP1 family of microtubule-associated proteins.Genome biology · 2006Review
- Cytoskeleton in action: lissencephaly, a neuronal migration disorder.Wiley interdisciplinary reviews. Developmental biologyReview
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For neuronal migration to occur, the cell must undergo morphological changes that require modifications of the cytoskeleton. Several different MAPs (microtubule-associated proteins) or actin-binding proteins are proposed to be involved in the migration of neurons. Therefore we have specifically analysed how two members of the MAP family, MAP1B and LIS1 (lissencephaly-related protein 1), interact with one another and participate in neuronal migration. Our results indicate that, in hippocampal neurons, MAP1B and LIS1 co-localize, associate and interact with each another. The interaction between these two MAPs is regulated by the phosphorylation of MAP1B. Furthermore, this interaction interferes with the association between LIS1 and the microtubule-dependent molecular motor, dynein. Clearly, the differential binding of these cytoskeletal proteins could regulate the functions attributed to the LIS1-dynein complex, including those related to extension of the neural processes necessary for neuronal migration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.