Evidence map›Paper›PMID 15759178›Full record

Trial reportSurgical endoscopy2005

Early results of a randomized multicenter trial comparing Prolene and VyproII mesh in bilateral endoscopic extraperitoneal hernioplasty (TEP).

S Bringman, S Wollert, J Osterberg, T Heikkinen

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 7 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. TEP for elective primary unilateral inguinal hernia repair in men: what do we know?Hernia : the journal of hernias and abdominal wall surgery · 2019
    Pooled it
  3. Pooled it
  4. Guideline
  5. Lightweight versus heavyweight in inguinal hernia repair: a meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2012
    Pooled it
  6. Pooled it
  7. European Hernia Society guidelines on the treatment of inguinal hernia in adult patients.Hernia : the journal of hernias and abdominal wall surgery · 2009
    Guideline
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Varying convalescence recommendations after inguinal hernia repair: a systematic scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Inguinal hernia repair: current surgical techniques.Langenbeck's archives of surgery · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

S BringmanCenter for Surgical Sciences, Karolinska Institutet, Sodertalje Hospital, SE-15286, Sodertalje, Sweden. sven.bringman@cfss.ki.se
S Wollert
J Osterberg
T Heikkinen
Karolinska Institutet · SEMora lasarett · SEOulu University Hospital · FIUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of mesh in inguinal hernia surgery has become increasingly popular despite the potentially harmful effects that foreign material may exert on human tissue. The purpose of this study was to compare the use of a lightweight mesh vs a standard hernia mesh in bilateral endoscopic hernioplasty.

methodsThis single-blinded multicenter trial, 140 men with bilateral inguinal hernias were randomized to undergo totally extraperitoneal endoscopic hernioplasty (TEP) with either Prolene or VyproII. The randomization and all data management were done via the Internet.

resultsA total of 139 patients were operated on as allocated. The follow-up was complete in 94% of the patients. The median (range) operating times were 85 min (45-140) and 73 min (35-165) for the Prolene and VyproII groups, respectively. (p = 0.01). The difference was due to uneven distribution of the allocated patients to study groups among individual surgeons. The time to return to work was similar (11 vs 9 days, p = 0.08). The time to return to normal daily activities was 19 days (1-133) in the Prolene group and 12.5 days (0-237) in the VyproII group (p = 0.06). There were no significant differences between the groups in their scores on the Visual Analogue Scale or SF-36 Health Scores during the 8-week follow-up.

conclusionsThe use of Prolene and VyproII meshes in bilateral endoscopic repair of inguinal hernia seems to result in similar short-term outcome and quality of life. However, there was a tendency toward faster return to normal activity among VyproII patients.

Indexed as

Polyglactin 910PolypropylenesSurgical MeshAdultAgedElasticityElective Surgical ProceduresEndoscopyEquipment DesignFollow-Up StudiesHernia, InguinalHumansIntraoperative ComplicationsMaleMiddle AgedPeritoneumPolyglactin 910PolypropylenesVyproII

Identifiers

PMID15759178
OpenAlexW2013628568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.