Evidence map›Paper›PMID 15759122›Full record

ReviewDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2005

[Programmed cell death in the retina. Molecular mechanisms and therapeutic strategies].

P Kermer, M Bähr

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Real-time in vivo imaging of retinal cell apoptosis after laser exposure.Investigative ophthalmology & visual science · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

P KermerNeurologische Klinik, Georg-August-Universität, Göttingen. pkermer@gwdg.de
M Bähr
University of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular suicide program (apoptosis) is important not only for many physiological processes spanning from embryonal development to aging but also for the pathogenesis and the course of a wide spectrum of diseases. Among these disorders are chronic neurodegenerative diseases including acquired and inherited degeneration of photoreceptors as well as retinal ganglion cells during retinitis pigmentosa, macular degeneration, optic neuritis, or glaucoma. In the following review we will address general pro- and antiapoptotic signal transduction cascades, their relevance for retinal degeneration focussing on retinal ganglion cells, and new therapeutic strategies evolving from these findings.

Indexed as

ApoptosisModels, BiologicalSignal TransductionAnimalsEye ProteinsGene Expression RegulationHumansRetinaRetinal DiseasesEye Proteins

Identifiers

PMID15759122
OpenAlexW89970626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.