Evidence map›Paper›PMID 15759084›Full record

ReviewMarine biotechnology (New York, N.Y.)

Atlantic cod trypsins: from basic research to practical applications.

Agústa Gudmundsdóttir, Helga Margrét Pálsdóttir

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Marine biotechnology (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 70 citations in OpenAlex.

  1. Review
  2. Cold-Adapted Proteases: An Efficient and Energy-Saving Biocatalyst.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Review
  5. Crustacean Proteases and Their Application in Debridement.Tropical life sciences research · 2020
    Article
  6. Article
  7. The yellowtail (Seriola quinqueradiata) genome and transcriptome atlas of the digestive tract.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018
    Article
  8. Review
  9. Article
  10. Article
  11. Potential use of Atlantic cod trypsin in biomedicine.BioMed research international · 2013
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Crystallization and preliminary X-ray diffraction studies of trypsin-like proteases from the gastric fluid of the marine crab Cancer pagurus.Acta crystallographica. Section F, Structural biology and crystallization communications · 2007
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Agústa GudmundsdóttirScience Institute, University of Iceland, Laeknagardi, Vatnsmýrarvegi 16, Reykjavík, IS-101, Iceland. ag@hi.is
Helga Margrét Pálsdóttir
University of Iceland · IS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atlantic cod trypsin I is an appropriate representative of the traditionally classified cold-adapted group I trypsins, and the recombinant form of cod trypsin Y is the only biochemically characterized member of the novel group III trypsins. Trypsin Y is adapted to lower temperatures than all other presently known trypsins. This review describes the basic characteristics of and practical uses for trypsins of Atlantic cod, as well as those of other organisms. Overexpression of the recombinant forms of cod trypsins I and Y in microorganisms is explained as well as the advantages of using site-directed mutagenesis to increase their stability toward autolysis and thermal inactivation. Trypsins appear to play a key role in the nutrition and development of marine fish. We discuss the potential use of cod trypsins as biomarkers to evaluate the nutritional status of cod larvae and describe the industrial applications of cod trypsin I and other trypsins.

Indexed as

BiotechnologyGene ExpressionModels, MolecularAdaptation, PhysiologicalAmino Acid SequenceAnimalsCold TemperatureEscherichia coliFisheriesFishesIcelandMolecular Sequence DataMutagenesis, Site-DirectedPichiaSequence AlignmentTrypsinTrypsin

Identifiers

PMID15759084
OpenAlexW2091174568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.