ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2005
Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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Who cites it
30 citing papers in PubMed, 103 citations in OpenAlex.
- Dopaminergic Neurons in the Zebrafish Subpallium Belong to the Extended Medial Amygdala.The Journal of comparative neurology · 2025Article
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- Development of the mouse anterior amygdalar radial unit marked by Lhx9-expression.Brain structure & function · 2021Article
- Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala.Brain structure & function · 2021Article
- Novel Perspectives on the Development of the Amygdala in Rodents.Frontiers in neuroanatomy · 2021Review
- A radial histogenetic model of the mouse pallial amygdala.Brain structure & function · 2020Article
- Histogenetic Radial Models as Aids to Understanding Complex Brain Structures: The Amygdalar Radial Model as a Recent Example.Frontiers in neuroanatomy · 2020Article
- DMRT5, DMRT3, and EMX2 Cooperatively RepressThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- PAX6 can substitute for LHX2 and override NFIA-induced astrogliogenesis in developing hippocampus in vivo.Journal of biosciences · 2018Article
- Cell migration in the developing rodent olfactory system.Cellular and molecular life sciences : CMLS · 2016Review
- Conserved localization of Pax6 and Pax7 transcripts in the brain of representatives of sarcopterygian vertebrates during development supports homologous brain regionalization.Frontiers in neuroanatomy · 2014Article
- Neural progenitors, patterning and ecology in neocortical origins.Frontiers in neuroanatomy · 2013Review
- Organization of the human fetal subpallium.Frontiers in neuroanatomy · 2013Article
- COUP-TFII controls amygdala patterning by regulating neuropilin expression.Development (Cambridge, England) · 2012Article
- Aging-associated modulation in the expression of Pax6 in mouse brain.Cellular and molecular neurobiology · 2012Article
- The avian subpallium: new insights into structural and functional subdivisions occupying the lateral subpallial wall and their embryological origins.Brain research · 2011Review
- Pax6 is required at the telencephalic pallial-subpallial boundary for the generation of neuronal diversity in the postnatal limbic system.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Toward a neurobiology of delusions.Progress in neurobiology · 2010Review
- A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei.Nature neuroscience · 2010Article
- Emx1-lineage progenitors differentially contribute to neural diversity in the striatum and amygdala.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The amygdaloid complex is a group of nuclei that are thought to originate from multiple sites of the dorsal and ventral telencephalic neuroepithelium. The mechanisms that regulate their development are essentially unknown. We studied the role of Pax6 and Emx2, two transcription factors that regulate regional specification and growth of the telencephalon, in the morphogenesis of the amygdaloid complex. We used a set of specific marker genes that identify distinct amygdaloid nuclei to analyze Pax6/Small eye and Emx2 knock-out mutant mouse brains. We found that there is a selective requirement for Pax6, but not Emx2, in the formation a subset of nuclei within the amygdaloid complex. Specifically, structures that were not previously considered to be developmentally linked, the nucleus of the lateral olfactory tract and the lateral, basolateral, and basomedial nuclei, all appear to have a common requirement for Pax6. Together, our findings provide new insights into the origins and mechanisms underlying the development of the amygdaloid complex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.