ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2005
Recurrent selection with reduced herbicide rates results in the rapid evolution of herbicide resistance in Lolium rigidum.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 230 citations in OpenAlex.
- The genetic architecture and spatiotemporal dynamics of adaptation across human-modified landscapes.The New phytologist · 2026Review
- A proof-of-concept experimental-theoretical model to predict pesticide resistance evolution.Heredity · 2025Article
- Interactions between prosulfocarb and trifluralin metabolism in annual ryegrass (Lolium rigidum).Pest management science · 2025Article
- Economical Evaluation of Reduced Herbicide Doses Application Rates to ControlPlants (Basel, Switzerland) · 2024Article
- Coupling machine learning and epidemiological modelling to characterise optimal fungicide doses when fungicide resistance is partial or quantitative.Journal of the Royal Society, Interface · 2023Article
- Enhanced production of water-soluble cinmethylin metabolites by Lolium rigidum populations with reduced cinmethylin sensitivity.Pest management science · 2022Article
- Cytochrome P450 CYP709C56 metabolizing mesosulfuron-methyl confers herbicide resistance in Alopecurus aequalis.Cellular and molecular life sciences : CMLS · 2022Article
- Rapid On-Farm Testing of Resistance inPlants (Basel, Switzerland) · 2021Article
- Recurrent Selection with Sub-Lethal Doses of Mesotrione Reduces Sensitivity inPlants (Basel, Switzerland) · 2021Article
- Review: evolutionary drivers of agricultural adaptation in Lolium spp.Pest management science · 2021Review
- Insights into the Role of Transcriptional Gene Silencing in Response to Herbicide-Treatments inInternational journal of molecular sciences · 2021Article
- The Effects of Succinate Dehydrogenase Inhibitor Fungicide Dose and Mixture on Development of Resistance inApplied and environmental microbiology · 2020Article
- Herbicide drift exposure leads to reduced herbicide sensitivity in Amaranthus spp.Scientific reports · 2020Article
- Diversified Resistance Mechanisms in Multi-ResistantFrontiers in plant science · 2020Article
- Investigation of physiological and molecular mechanisms conferring diurnal variation in auxinic herbicide efficacy.PloS one · 2020Article
- Omics Potential in Herbicide-Resistant Weed Management.Plants (Basel, Switzerland) · 2019Review
- 10,000-Times Diluted Doses of ACCase-Inhibiting Herbicides Can Permanently Change the Metabolomic Fingerprint of SusceptiblePlants (Basel, Switzerland) · 2019Article
- The evolutionary origins of pesticide resistance.Biological reviews of the Cambridge Philosophical Society · 2019Article
- Sequencing the Plastid Genome of Giant Ragweed (Frontiers in plant science · 2019Article
- Response of Amaranthus spp. following exposure to sublethal herbicide rates via spray particle drift.PloS one · 2019Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has been much debate regarding the potential for reduced rates of herbicide application to accelerate evolution of herbicide resistance. We report a series of experiments that demonstrate the potential for reduced rates of the acetyl-co enzyme A carboxylase (ACCase)-inhibiting herbicide diclofop-methyl to rapidly select for resistance in a susceptible biotype of Lolium rigidum. Thirty-six percent of individuals from the original VLR1 population survived application of 37.5 g diclofop-methyl ha(-1) (10% of the recommended field application rate). These individuals were grown to maturity and bulk-crossed to produce the VLR1 low dose-selected line VLR1 (0.1). Subsequent comparisons of the dose-response characteristics of the original and low dose-selected VLR1 lines demonstrated increased tolerance of diclofop-methyl in the selected line. Two further rounds of selection produced VLR1 lines that were resistant to field-applied rates of diclofop-methyl. The LD50 (diclofop-methyl dose required to cause 50% mortality) of the most resistant line was 56-fold greater than that of the original unselected VLR1 population, indicating very large increases in mean population survival after three cycles of selection. In vitro ACCase inhibition by diclofop acid confirmed that resistance was not due to an insensitive herbicide target-site. Cross-resistance studies showed increases in resistance to four herbicides: fluazifop-P-butyl, haloxyfop-R-methyl, clethodim and imazethapyr. The potential genetic basis of the observed response and implications of reduced herbicide application rates for management of herbicide resistance are discussed.
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