ArticleBritish journal of cancer2005
Trends in UK cancer trials: results from the UK Coordinating Committee for Cancer Research National Register of Cancer Trials.
Article in British journal of cancer, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Constructing within and between hospital physician social networks for modeling physician research participation.BMC medical research methodology · 2023Article
- Placental, Foetal, and Maternal Serum Metabolomic Profiles in Pregnancy-Associated Cancer: Walker-256 Tumour Model in a Time-Course Analysis.International journal of molecular sciences · 2023Article
- Availability of Results of Trials Studying Pancreatic Adenocarcinoma over the Past 10 Years.The oncologist · 2022Article
- Assessment of transparency and selective reporting of interventional trials studying colorectal cancer.BMC cancer · 2022Article
- Availability of results of interventional studies assessing colorectal cancer from 2013 to 2020.PloS one · 2022Article
- Walker-256 Tumour-Induced Cachexia Altered Liver Metabolomic Profile and Function in Weanling and Adult Rats.Metabolites · 2021Article
- Serum and MuscleNutrients · 2020Article
- Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia.Cancers · 2020Article
- Leucine-rich diet induces a shift in tumour metabolism from glycolytic towards oxidative phosphorylation, reducing glucose consumption and metastasis in Walker-256 tumour-bearing rats.Scientific reports · 2019Article
- Maternal Leucine-Rich Diet Minimises Muscle Mass Loss in Tumour-bearing Adult Rat Offspring by Improving the Balance of Muscle Protein Synthesis and Degradation.Biomolecules · 2019Article
- A leucine-rich diet modulates the mTOR cell signalling pathway in the gastrocnemius muscle under different Walker-256 tumour growth conditions.BMC cancer · 2019Article
- Article
- Facilitating access to health research through a participatory research register: a feasibility study in outpatient clinics.Pilot and feasibility studies · 2018Article
- Nutritional leucine supplementation attenuates cardiac failure in tumour-bearing cachectic animals.Journal of cachexia, sarcopenia and muscle · 2016Article
- Leucine-rich diet alters theBMC cancer · 2016Article
- Metformin treatment modulates the tumour-induced wasting effects in muscle protein metabolism minimising the cachexia in tumour-bearing rats.BMC cancer · 2016Article
- Dietary leucine supplementation minimises tumour-induced damage in placental tissues of pregnant, tumour-bearing rats.BMC cancer · 2016Article
- The progression of cell death affects the rejection of allogeneic tumors in immune-competent mice - implications for cancer therapy.Frontiers in immunology · 2014Article
- Light aerobic physical exercise in combination with leucine and/or glutamine-rich diet can improve the body composition and muscle protein metabolism in young tumor-bearing rats.Journal of physiology and biochemistry · 2012Article
- Achieving sufficient accrual to address the primary endpoint in phase III clinical trials from U.S. Cooperative Oncology Groups.Clinical cancer research : an official journal of the American Association for Cancer Research · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to study trends in the design and conduct of randomised controlled trials (RCTs) in cancer in the UK, using the UK Coordinating Committee for Cancer Research (UKCCCR) National Register of Cancer Trials (NRCT). We conducted a descriptive survey of 520 UK RCTs in cancer that were registered on the UKCCCR NRCT. All trials had been initiated between 1971 and 2000. Trials on the NRCT have been conducted in a wide variety of cancer types, but with a third in breast (22%) or lung cancer (11%). They have largely been funded by the UK public and charity sectors. Overall, there has been a sustained rise in the total numbers of patients entering UK cancer trials over time with a trend towards larger, multicentre trials, greater recruitment targets and a marked reduction in the average time taken to complete trials. Trends in the design and conduct of noncommercial cancer RCTs from 1971 to 2000 are encouraging. It will be interesting to see how they develop in light of the implementation of recent national initiatives regarding cancer clinical trials in the UK.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.