ArticleWorld journal of gastroenterology2005
Human papillomavirus in squamous cell carcinoma of esophagus in a high-risk population.
Article in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- HPV prevalence in esophageal cancer: an updated systematic review and meta-analysis.Frontiers in microbiology · 2026Pooled it
- Pooled it
- Association between human papillomavirus (HPV) and oesophageal squamous cell carcinoma: a meta-analysis.Epidemiology and infection · 2014Pooled it
- The aetiological role of human papillomavirus in oesophageal squamous cell carcinoma: a meta-analysis.PloS one · 2013Pooled it
- Improving esophageal cancer screening across the globe: Translating knowledge into action.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Review
- Review
- HPV18 E6 inhibits α-ketoglutarate-induced pyroptosis of esophageal squamous cell carcinoma cells via the P53/MDH1/ROS/GSDMC pathway.FEBS open bio · 2023Article
- Human Papillomavirus Infection and Oropharyngeal and Gastrointestinal Cancers: A Causal Relationship?Diseases (Basel, Switzerland) · 2022Review
- Oesophageal carcinoma: The prevalence of DNA tumour viruses and therapy.Tumour virus research · 2022Review
- Study to investigate the prevalence of human papillomavirus in Barrett's oesophagus using a novel screening methodology.BMJ open gastroenterology · 2022Article
- Evidence of High-Risk Human Papillomavirus in Esophageal Cancer in East Azerbaijan Province, Northwest of Iran.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022Article
- A transcriptomic analysis of malignant transformation of human embryonic esophageal epithelial cells by HPV18 E6E7.Translational cancer research · 2020Article
- Prevalence and Association of Human Papillomavirus with Esophageal Squamous Cell Carcinoma in Iran: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2019Review
- Effects of microRNA-374 on proliferation, migration, invasion, and apoptosis of human SCC cells by targeting Gadd45a through P53 signaling pathway.Bioscience reports · 2017Article
- Human papillomavirus and gastrointestinal cancer in Iranian population: A systematic review and meta-analysis.Caspian journal of internal medicine · 2017Review
- Population attributable fraction of Esophageal squamous cell carcinoma due to smoking and alcohol in Uganda.BMC cancer · 2016Article
- Prevalence of human papillomavirus in esophageal carcinoma in Tangshan, China.World journal of gastroenterology · 2015Article
- Human papilloma virus infection in non-cancerous versus normal esophageal tissue samples by endoscopy.Caspian journal of internal medicine · 2015Article
- Inhibition of human esophageal squamous cell carcinomas by targeted silencing of tumor enhancer genes: an overview.Cancer biology & medicine · 2014Review
- Gene chip technology used in the detection of HPV infection in esophageal cancer of Kazakh Chinese in Xinjiang Province.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2014Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the relation of human papillomavirus (HPV) and esophageal squamous cell carcinoma (ESCC) in Iranian patients as compared to normal controls.
methodsUsing MY09/MY11 consensus primers, we compared the prevalence of a HPV L1 gene in tumor tissues from 38 ESCC cases and biopsied tissues from 38 endoscopically normal Iranian individuals. We also compared the presence of HPV16 and HPV18 in the same samples using type-specific E6/E7 primers.
resultsFourteen (36.8%) of the 38 ESCC samples but only 5 (13.2%) of the 38 control samples were positive for the HPV L1 gene (P = 0.02). Five (13.2%) of the ESCC samples but none of the control samples were positive for the HPV16 E6/E7 gene (P = 0.05). Three (7.9%) of the ESCC samples and 5 (13.2%) of the control samples were positive for the HPV18 E6/E7 gene (P = 0.71).
conclusionOur data are consistent with HPV DNA studies conducted in other high-risk areas for ESCC. HPV should be considered as a potential factor contributing to the high incidence of ESCC in Iran and other high-incidence areas of the world.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.