Evidence map›Paper›PMID 15754404›Full record

ArticleWorld journal of gastroenterology2005

Role of the intracellular receptor domain of gp130 (exon 17) in human inflammatory bowel disease.

Christoph-J Auernhammer, Kathrin Zitzmann, Fabian Schnitzler, Julia Seiderer, Peter Lohse, George Vlotides, Dieter Engelhardt, Michael Sackmann, Burkhard Goke, Thomas Ochsenkuhn

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Christoph-J AuernhammerDepartment of Internal Medicine II, Klinikum Grosshadern, Ludwig-Maximilians-University, Marchioninistr 15, D-81377 Munich, Germany. christoph.auernhammer@med.uni-muenchen.de
Kathrin Zitzmann
Fabian Schnitzler
Julia Seiderer
Peter Lohse
George Vlotides
Dieter Engelhardt
Michael Sackmann
Burkhard Goke
Thomas Ochsenkuhn
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the role of the intracellular receptor domain of gp130 in human inflammatory bowel disease (IBD).

methodsWe amplified and sequenced the complete exon 17 of the human gp130 gene in 146 patients with IBD. According to clinical and histopathological signs, the 146 patients with IBD were classified as having Crohn's disease (n = 73) or ulcerative colitis (n = 63), or as indeterminate status (n = 10).

resultsNo mutations in exon 17 of the gp130 gene could be detected in any of the 146 patients with IBD examined.

conclusionThere is no evidence that mutations in exon 17 of the gp130 gene are involved in the pathogenesis of human IBD.

Indexed as

AdultAgedAntigens, CDColitis, UlcerativeCrohn DiseaseCytokine Receptor gp130ExonsFemaleHumansMaleMembrane GlycoproteinsMiddle AgedProtein Structure, TertiaryAntigens, CDCytokine Receptor gp130IL6ST protein, humanMembrane Glycoproteins

Identifiers

PMID15754404
PMCPMC4250713
OpenAlexW1997851837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.