ReviewThe Journal of experimental medicine2005
Private aspects of heterologous immunity.
Review in The Journal of experimental medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-specific immunological effects of selected routine childhood immunisations: systematic review.BMJ (Clinical research ed.) · 2016Pooled it
- Trial
- Mechanisms governing bystander activation of T cells.Frontiers in immunology · 2024Review
- Significance of bystander T cell activation in microbial infection.Nature immunology · 2022Review
- Phenotypes and Functions of SARS-CoV-2-Reactive T Cells.Molecules and cells · 2021Review
- Cross-Reactive Effects of Vaccines: Heterologous Immunity between Tetanus and Chlamydia.Vaccines · 2020Article
- Article
- Local immunodeficiency: Minimal networks and stability.Mathematical biosciences · 2019Article
- Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections.Frontiers in immunology · 2019Review
- The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains.Frontiers in immunology · 2019Article
- Weighted lambda superstrings applied to vaccine design.PloS one · 2019Article
- Article
- Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines.PloS one · 2016Article
- Antigenic cooperation among intrahost HCV variants organized into a complex network of cross-immunoreactivity.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- The two faces of heterologous immunity: protection or immunopathology.Journal of leukocyte biology · 2014Review
- CD8(+) T-Cell Responses in Acute Hepatitis C Virus Infection.Frontiers in immunology · 2014Review
- Two distinct functional patterns of hepatitis C Virus (HCV)-specific T cell responses in seronegative, aviremic patients.PloS one · 2013Article
- Temporal variations in the hepatitis C virus intrahost population during chronic infection.Journal of virology · 2011Article
- Heterologous immunity: immunopathology, autoimmunity and protection during viral infections.Autoimmunity · 2011Review
- CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Clinical manifestations of viral infections are highly variable, both in type and severity, among individual patients. Differences in host genetics and in dose and route of infection contribute to this variability but do not fully explain it. New studies now show that each subject's history of past infections individualizes the memory T cell pool. Private T cell receptor specificities of these preexisting memory T cell populations influence both disease severity and outcome of subsequent, unrelated virus infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.