ArticleJournal of clinical microbiology2005
Confirming positive results of nucleic acid amplification tests (NAATs) for Chlamydia trachomatis: all NAATs are not created equal.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00618449 (Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Self-Collected versus Clinician-Collected Sampling for Chlamydia and Gonorrhea Screening: A Systemic Review and Meta-Analysis.PloS one · 2015Pooled it
- Diagnostic characteristics of tests for ocular Chlamydia after mass azithromycin distributions.Investigative ophthalmology & visual science · 2012Trial
- Ribosomal RNA evidence of ocular Chlamydia trachomatis infection following 3 annual mass azithromycin distributions in communities with highly prevalent trachoma.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012Trial
- Laboratory detection methods for Chlamydia trachomatis infection in children: a review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Review
- ExploringFrontiers in public health · 2025Article
- Alternate Nucleic Acid Targets Can Be Used To Create a Composite Standard To Evaluate Clinical Performance of Nucleic Acid Amplification Tests.Journal of clinical microbiology · 2019Article
- Chlamydia trachomatis IgG3 seropositivity is associated with gastroschisis.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
- Lymphogranuloma venereum: diagnostic and treatment challenges.Infection and drug resistance · 2015Review
- Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae--2014.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2014Article
- Self-collected versus clinician-collected sampling for sexually transmitted infections: a systematic review and meta-analysis protocol.Systematic reviews · 2013Article
- Cost-effectiveness of screening men in Maricopa County jails for chlamydia and gonorrhea to avert infections in women.Sexually transmitted diseases · 2013Article
- Genital Chlamydia trachomatis: an update.The Indian journal of medical research · 2013Review
- Comparison of three assays for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in SurePath Pap samples and the role of pre- and postcytology testing.Journal of clinical microbiology · 2012Article
- Guidelines for the use of molecular biological methods to detect sexually transmitted pathogens in cases of suspected sexual abuse in children.Methods in molecular biology (Clifton, N.J.) · 2012Article
- Risk factors for ocular chlamydia after three mass azithromycin distributions.PLoS neglected tropical diseases · 2011Article
- Correlation of clinical trachoma and infection in Aboriginal communities.PLoS neglected tropical diseases · 2011Article
- Molecular Diagnosis of Sexually Transmitted Chlamydia trachomatis in the United States.ISRN obstetrics and gynecology · 2011Article
- Antibiotic resistance in Chlamydiae.Future microbiology · 2010Review
- Medical and legal implications of testing for sexually transmitted infections in children.Clinical microbiology reviews · 2010Review
- Chlamydia trachomatis today: treatment, detection, immunogenetics and the need for a greater global understanding of chlamydial disease pathogenesis.Drugs of today (Barcelona, Spain : 1998) · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Centers for Disease Control and Prevention recommended confirming positive screening tests for Chlamydia trachomatis when positive predictive values are <90%. It is accepted that less sensitive tests (i.e., culture and immunoassays) should not be used to confirm the results of more sensitive nucleic acid amplification tests (NAATs). We show that the same principle applies when NAATs are used for confirmation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.