ArticleJournal of clinical microbiology2005
Molecular subtyping and characterization of bovine and human Streptococcus agalactiae isolates.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Zoonotic Approach toInternational journal of microbiology · 2026Article
- How GBS Got Its Hump: Genomic Analysis of Group BPathogens (Basel, Switzerland) · 2022Article
- Antimicrobial and antibiofilm potentials of cinnamon oil and silver nanoparticles against Streptococcus agalactiae isolated from bovine mastitis: new avenues for countering resistance.BMC veterinary research · 2021Article
- Population Gene Introgression and High Genome Plasticity for the Zoonotic Pathogen Streptococcus agalactiae.Molecular biology and evolution · 2019Article
- Potential group B Streptococcus interspecies transmission between cattle and people in Colombian dairy farms.Scientific reports · 2019Article
- Genomic Insights Into the Distribution and Evolution of Group B Streptococcus.Frontiers in microbiology · 2019Review
- Phylogenetic, comparative genomic and structural analyses of human Streptococcus agalactiae ST485 in China.BMC genomics · 2018Article
- High Incidence of PathogenicFrontiers in microbiology · 2018Article
- Group B Streptococcal Colonization, Molecular Characteristics, and Epidemiology.Frontiers in microbiology · 2018Review
- Streptococcus agalactiae Serotype IV in Humans and Cattle, Northern EuropeEmerging infectious diseases · 2016Article
- Genetic and pathogenic difference between Streptococcus agalactiae serotype Ia fish and human isolates.BMC microbiology · 2016Article
- Association between genotypic diversity and biofilm production in group B Streptococcus.BMC microbiology · 2016Article
- Novel IgG-Degrading Enzymes of the IgdE Protease Family Link Substrate Specificity to Host Tropism of Streptococcus Species.PloS one · 2016Article
- Antimicrobial susceptibility profiles, serotype distribution and virulence determinants among invasive, non-invasive and colonizing Streptococcus agalactiae (group B streptococcus) from Malaysian patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Article
- Survey of immunological features of the alpha-like proteins of Streptococcus agalactiae.Clinical and vaccine immunology : CVI · 2015Review
- Pilus distribution among lineages of group b streptococcus: an evolutionary and clinical perspective.BMC microbiology · 2014Article
- Transcriptomic and genomic evidence for Streptococcus agalactiae adaptation to the bovine environment.BMC genomics · 2013Article
- Molecular epidemiology of mastitis pathogens of dairy cattle and comparative relevance to humans.Journal of mammary gland biology and neoplasia · 2011Review
- Comparative genomics and the role of lateral gene transfer in the evolution of bovine adapted Streptococcus agalactiae.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2011Article
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9 authors.
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Abstract
Streptococcus agalactiae causes severe invasive disease in humans and mastitis in cattle. Temporally matched bovine milk isolates and clinical human invasive isolates (52 each) collected in New York State over 18 months were characterized by molecular subtyping and phenotypic methods to probe the interspecies transmission potential of this species. EcoRI ribotyping differentiated 17 ribotypes, and DNA sequencing of the housekeeping gene sodA and the putative virulence gene hylB differentiated 7 and 17 allelic types, respectively. Human and bovine isolates were not randomly distributed between ribotypes or hylB and sodA clusters. The combined analysis of all subtyping data allowed the differentiation of 39 clonal groups; 26 groups contained only bovine isolates, and 2 groups contained both human and bovine isolates. The EcoRI ribotype diversity among bovine isolates (Simpson's numerical index of discrimination [mean +/- standard deviation], 0.90 +/- 0.05) being significantly higher than that among human isolates (0.42 +/- 0.15) further supports that these isolates represent distinct populations. Eight human isolates, but no bovine isolates, showed an IS1548 transposon insertion in hylB, which encodes a hyaluronidase. Based on data for 43 representative isolates, human isolates, on average, showed lower hyaluronidase activities than bovine isolates. Isolates with the IS1548 insertion in hylB showed no hyaluronidase activity. Human and bovine isolates did not differ in their abilities to invade HeLa human epithelial cells. Our data show that (i) EcoRI ribotyping, combined with hylB and sodA sequencing, provides a discriminatory subtype analysis of S. agalactiae; (ii) most human invasive and bovine S. agalactiae isolates represent distinct subtypes, suggesting limited interspecies transmission; and (iii) hyaluronidase activity is not required for all human infections.
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