ArticleJournal of clinical microbiology2005
Characterization of rotavirus strains in a Danish population: high frequency of mixed infections and diversity within the VP4 gene of P[8] strains.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 42 citations in OpenAlex.
- Genetic and antigenic diversity of rotavirus A in faeces from Danish pigs.Virus evolution · 2026Article
- Post-rotavirus vaccine intussusception in identical twins: A case report.Human vaccines & immunotherapeutics · 2016Article
- Predominance of genotype P[9]G3 in rotavirus gastroenteritis in Polish children.Archives of medical science : AMS · 2015Article
- Molecular genotyping and quantitation assay for rotavirus surveillance.Journal of virological methods · 2015Article
- Sequence analysis of human rotavirus strains: comparison of clinical isolates from Northern and Southern Italy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Burden of community-acquired and nosocomial rotavirus gastroenteritis in the pediatric population of Western Europe: a scoping review.BMC infectious diseases · 2012Article
- Molecular Epidemiology of Rotavirus Strains Circulating among Children with Gastroenteritis in Iran.Iranian journal of pediatrics · 2012Article
- Characterization of group A rotavirus infections in adolescents and adults from Pune, India: 1993-1996 and 2004-2007.Journal of medical virology · 2010Article
- Detection and genotyping of human rotavirus VP4 and VP7 genes by reverse transcriptase PCR and reverse hybridization.Journal of clinical microbiology · 2009Article
- Emergence of unusual human rotavirus strains in Salento, Italy, during 2006-2007.BMC infectious diseases · 2009Article
- Occurrence of group A rotavirus mixed P genotypes infections in children living in Goiânia-Goiás, Brazil.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2008Article
- Development of a microtiter plate hybridization-based PCR-enzyme-linked immunosorbent assay for identification of clinically relevant human group A rotavirus G and P genotypes.Journal of clinical microbiology · 2008Article
- Prevalence of enteropathogenic viruses and molecular characterization of group A rotavirus among children with diarrhea in Dar es Salaam Tanzania.BMC public health · 2007Article
- Molecular epidemiology of rotavirus in Central and Southeastern Europe.Journal of clinical microbiology · 2007Article
- Molecular characterization of a new variant of rotavirus P[8]G9 predominant in a sentinel-based survey in central Italy.Journal of clinical microbiology · 2007Article
- Molecular epidemiology of group A rotaviruses in water sources and selected raw vegetables in southern Africa.Applied and environmental microbiology · 2006Article
- Human rotavirus serotype G9, São Paulo, Brazil, 1996-2003.Emerging infectious diseases · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We characterized the G and P types from 162 rotavirus-positive stool specimens collected from 162 persons in Denmark (134 children and 28 adults) with acute diarrhea in 1998, 2000, and 2002. Samples were obtained during outpatient consultations (73%) and from hospitalized patients (27%). Although more than 20 different G-P combinations were identified, only 52% represented the globally most common types G1P[8], G2P[4], and G4P[8]. The G9 genotype, which is emerging worldwide, was identified in 12% of all samples. Twenty-one percent of the samples were of mixed genotypic origin, which is the highest frequency reported in any European population. The standard reverse transcription-PCR methods initially failed to identify a considerable fraction of the rotavirus P strains due to mutations at the VP4 primer-binding sites of P[8] strains. The application of a degenerate P[8] primer resulted in typing of most VP4 strains. There was considerable year-to-year variation among the circulating G-P types, and whereas G1P[8] was predominant in 1998 (42% of samples) and 2002 (26%), G2P[4] was the strain that was most frequently detected in 2000 (26% of samples). Our findings might implicate challenges for rotavirus vaccine implementation in a European population and underscore the importance of extensive strain surveillance prior to, during, and after introduction of any vaccine candidate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.