ArticleApplied and environmental microbiology2005
Signal transduction by Tga3, a novel G protein alpha subunit of Trichoderma atroviride.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 129 citations in OpenAlex.
- Fused expression of Sm1-Chit42 proteins for synergistic mycoparasitic response of Trichoderma afroharzianum on Botrytis cinerea.Microbial cell factories · 2023Article
- Transcriptomic Response ofJournal of fungi (Basel, Switzerland) · 2023Article
- Circadian oscillations ineLife · 2022Article
- cAMP Signalling Pathway in Biocontrol Fungi.Current issues in molecular biology · 2022Review
- Review
- DecipheringJournal of fungi (Basel, Switzerland) · 2021Review
- Early transcriptomic response of the mycoparasiteBioresources and bioprocessing · 2021Article
- Gα3 subunit Thga3 positively regulates conidiation, mycoparasitism, chitinase activity, and hydrophobicity of Trichoderma harzianum.AMB Express · 2020Article
- Review
- Bioactive Secondary Metabolites fromMicroorganisms · 2020Review
- Chemotropism Assays for Plant Symbiosis and Mycoparasitism Related Compound Screening inFrontiers in microbiology · 2020Article
- Massive lateral transfer of genes encoding plant cell wall-degrading enzymes to the mycoparasitic fungus Trichoderma from its plant-associated hosts.PLoS genetics · 2018Article
- New Genomic Approaches to Enhance Biomass Degradation by the Industrial FungusInternational journal of genomics · 2018Review
- Necrotrophic Mycoparasites and Their Genomes.Microbiology spectrum · 2017Review
- The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species.Microbiology and molecular biology reviews : MMBR · 2016Review
- Identification of mycoparasitism-related genes in Clonostachys rosea 67-1 active against Sclerotinia sclerotiorum.Scientific reports · 2015Article
- Article
- Comparative analysis of the repertoire of G protein-coupled receptors of three species of the fungal genus Trichoderma.BMC microbiology · 2013Article
- Signaling governed by G proteins and cAMP is crucial for growth, secondary metabolism and sexual development in Fusarium fujikuroi.PloS one · 2013Article
- Trichoderma-plant-pathogen interactions: advances in genetics of biological control.Indian journal of microbiology · 2012Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trichoderma species are used commercially as biocontrol agents against a number of phytopathogenic fungi due to their mycoparasitic characterisitics. The mycoparasitic response is induced when Trichoderma specifically recognizes the presence of the host fungus and transduces the host-derived signals to their respective regulatory targets. We made deletion mutants of the tga3 gene of Trichoderma atroviride, which encodes a novel G protein alpha subunit that belongs to subgroup III of fungal Galpha proteins. Deltatga3 mutants had changes in vegetative growth, conidiation, and conidial germination and reduced intracellular cyclic AMP levels. These mutants were avirulent in direct confrontation assays with Rhizoctonia solani or Botrytis cinerea, and mycoparasitism-related infection structures were not formed. When induced with colloidal chitin or N-acetylglucosamine in liquid culture, the mutants had reduced extracellular chitinase activity even though the chitinase-encoding genes ech42 and nag1 were transcribed at a significantly higher rate than they were in the wild type. Addition of exogenous cyclic AMP did not suppress the altered phenotype or restore mycoparasitic overgrowth, although it did restore the ability to produce the infection structures. Thus, T. atroviride Tga3 has a general role in vegetative growth and can alter mycoparasitism-related characteristics, such as infection structure formation and chitinase gene expression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.