ArticleApplied and environmental microbiology2005
Rapid acyl-homoserine lactone quorum signal biodegradation in diverse soils.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Endogenous quorum sensing orchestrates microbial social behaviors for anaerobic digestion adaptation to temperature reduction.Environmental microbiome · 2026Article
- Synthetic microbiology in sustainability applications.Nature reviews. Microbiology · 2024Review
- Growth-Stimulatory Effect of Quorum Sensing Signal MoleculeFrontiers in microbiology · 2020Article
- The biological role of N-acyl-homoserine lactone-based quorum sensing (QS) in EPS production and microbial community assembly during anaerobic granulation process.Scientific reports · 2018Article
- Sorption characteristics ofRSC advances · 2018Article
- Deciphering Physiological Functions of AHL Quorum Quenching Acylases.Frontiers in microbiology · 2017Review
- Article
- Real-time monitoring of quorum sensing in 3D-printed bacterial aggregates using scanning electrochemical microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Plant responses to bacterial N-acyl L-homoserine lactones are dependent on enzymatic degradation to L-homoserine.ACS chemical biology · 2014Article
- Bacterial signaling ecology and potential applications during aquatic biofilm construction.Microbial ecology · 2014Review
- The role of quorum sensing signalling in EPS production and the assembly of a sludge community into aerobic granules.The ISME journal · 2014Article
- You are what you talk: quorum sensing induces individual morphologies and cell division modes in Dinoroseobacter shibae.The ISME journal · 2013Article
- Determination of whether quorum quenching is a common activity in marine bacteria by analysis of cultivable bacteria and metagenomic sequences.Applied and environmental microbiology · 2012Article
- Characterization of quorum sensing and quorum quenching soil bacteria isolated from Malaysian tropical montane forest.Sensors (Basel, Switzerland) · 2012Article
- Bacterial competition: surviving and thriving in the microbial jungle.Nature reviews. Microbiology · 2010Review
- Two dissimilar N-acyl-homoserine lactone acylases of Pseudomonas syringae influence colony and biofilm morphology.Applied and environmental microbiology · 2009Article
- Article
- Rapid screening of quorum-sensing signal N-acyl homoserine lactones by an in vitro cell-free assay.Applied and environmental microbiology · 2008Article
- Complete genome sequence of Nitrosospira multiformis, an ammonia-oxidizing bacterium from the soil environment.Applied and environmental microbiology · 2008Article
- Sensitive whole-cell biosensor suitable for detecting a variety of N-acyl homoserine lactones in intact rhizosphere microbial communities.Applied and environmental microbiology · 2007Article
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Authors and funding
2 authors.
Funding
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Abstract
Signal degradation impacts all communications. Although acyl-homoserine lactone (acyl-HSL) quorum-sensing signals are known to be degraded by defined laboratory cultures, little is known about their stability in nature. Here, we show that acyl-HSLs are biodegraded in soils sampled from diverse U.S. sites and by termite hindgut contents. When amended to samples at physiologically relevant concentrations, 14C-labeled acyl-HSLs were mineralized to 14CO2 rapidly and, at most sites examined, without lag. A lag-free turf soil activity was characterized in further detail. Heating or irradiation of the soil prior to the addition of radiolabel abolished mineralization, whereas protein synthesis inhibitors did not. Mineralization exhibited an apparent Km of 1.5 microM acyl-HSL, ca. 1,000-fold lower than that reported for a purified acyl-HSL lactonase. Under optimal conditions, acyl-HSL degradation proceeded at a rate of 13.4 nmol x h(-1) x g of fresh weight soil(-1). Bioassays established that the final extent of signal inactivation was greater than for its full conversion to CO2 but that the two processes were well coupled kinetically. A most probable number of 4.6 x 10(5) cells . g of turf soil(-1) degraded physiologically relevant amounts of hexanoyl-[1-14C]HSL to 14CO2. It would take chemical lactonolysis months to match the level of signal decay achieved in days by the observed biological activity. Rapid decay might serve either to quiet signal cross talk that might otherwise occur between spatially separated microbial aggregates or as a full system reset. Depending on the context, biological signal decay might either promote or complicate cellular communications and the accuracy of population density-based controls on gene expression in species-rich ecosystems.
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