ArticleImmunogenetics2005
Characterisation of a cluster of TRIM-B30.2 genes in the chicken MHC B locus.
Article in Immunogenetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Evolution and expression of the duck TRIM gene repertoire.Frontiers in immunology · 2023Article
- Innate immune genes of the chicken MHC and related regions.Immunogenetics · 2022Review
- Fourth Report on Chicken Genes and Chromosomes 2022.Cytogenetic and genome research · 2022Review
- Pattern Recognition Receptor Signaling and Innate Responses to Influenza A Viruses in the Mallard Duck, Compared to Humans and Chickens.Frontiers in cellular and infection microbiology · 2020Review
- Genetic Mutation Analysis of High and Low IgY Chickens by Capture Sequencing.Animals : an open access journal from MDPI · 2019Article
- Brief review of the chicken Major Histocompatibility Complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance.Poultry science · 2016Review
- Signatures of Crested Ibis MHC Revealed by Recombination Screening and Short-Reads Assembly Strategy.PloS one · 2016Article
- Duck TRIM27-L enhances MAVS signaling and is absent in chickens and turkeys.Molecular immunology · 2015Article
- Sequence of a complete chicken BG haplotype shows dynamic expansion and contraction of two gene lineages with particular expression patterns.PLoS genetics · 2014Article
- The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV).Immunogenetics · 2013Article
- Identification and characterization of multiple TRIM proteins that inhibit hepatitis B virus transcription.PloS one · 2013Article
- Extended sequence of the turkey MHC B-locus and sequence variation in the highly polymorphic B-G loci.Immunogenetics · 2011Article
- Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish.PloS one · 2011Article
- Molecular characterization and expression pattern of tripartite motif protein 39 in Gallus gallus with a complete PRY/SPRY domain.International journal of molecular sciences · 2011Article
- Fish 'n' TRIMs.Journal of biology · 2009Review
- Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties.BMC evolutionary biology · 2008Article
- The major histocompatibility complex (Mhc) class IIB region has greater genomic structural flexibility and diversity in the quail than the chicken.BMC genomics · 2006Article
- Relationship between SPRY and B30.2 protein domains. Evolution of a component of immune defence?Immunology · 2005Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have identified and characterised a cluster of six TRIM-B30.2 genes flanking the chicken BF/BL region of the B complex. The TRIM-B30.2 proteins are a subgroup of the TRIM protein family containing the tripartite motif (TRIM), consisting of a RING domain, a B-box and a coiled coil region, and a B30.2-like domain. In humans, a cluster of seven TRIM-B30.2 genes has been characterised within the MHC on Chromosome 6p21.33. Among the six chicken TRIM-B30.2 genes two are orthologous to those of the human MHC, and two (TRIM41 and TRIM7) are orthologous to human genes located on Chromosome 5. In humans, these last two genes are adjacent to GNB2L1, a guanine nucleotide-binding protein gene, the ortholog of the chicken c12.3 gene situated in the vicinity of the TRIM-B30.2 genes. This suggests that breakpoints specific to mammals have occurred and led to the remodelling of their MHC structure. In terms of structure, like their mammalian counterparts, each chicken gene consists of five coding exons; exon 1 encodes the RING domain and the B-box, exons 2, 3 and 4 form the coiled-coil region, and the last exon represents the B30.2-like domain. Phylogenetic analysis led us to assume that this extended BF/BL region may be similar to the human extended class I region, because it contains a cluster of BG genes sharing an Ig-V like domain with the BTN genes (Henry et al. 1997a) and six TRIM-B30.2 genes containing the B30.2-like domain, shared with the TRIM-B30.2 members and the BTN genes.
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