Evidence map›Paper›PMID 15743729›Full record

Trial reportEnvironmental health perspectives2005

Racial differences in exposure to environmental tobacco smoke among children.

Stephen E Wilson, Robert S Kahn, Jane Khoury, Bruce P Lanphear

2 registry-linked trialsAbstract readClinical TrialComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Environmental health perspectives, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00006565 phase3completednot on this map

Randomized Trial to Reduce Environmental Tobacco Smoke in Children With Asthma

TypeinterventionalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran2000 to 2004Enrolled225ConditionsAsthma, Lung DiseasesArmsHEPA Air Cleaner, Placebo Filtration Unit
NCT00395096 completednot on this mapstarted 2006, after this paper: background citation

Environmental Exposures, NOS Genes, and Exhaled Nitric Oxide in Pediatric Asthma

TypeobservationalSponsorChildren's Hospital Medical Center, CincinnatiRan2006 to 2008Enrolled225ConditionsAsthma
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. The Diverging Trend in Exposure to Environmental Tobacco Smoke Among US Children.Journal of racial and ethnic health disparities · 2024
    Article
  6. A Comparison of Measured Airborne and Self-Reported Secondhand Smoke Exposure in the MADRES Pregnancy Cohort Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  7. Article
  8. Article
  9. The Associations ofInternational journal of environmental research and public health · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Caring for Young Children with Asthma: Perspectives from Urban Community Health Centers.Journal of urban health : bulletin of the New York Academy of Medicine · 2017
    Article
  14. Comparison of secondhand smoke exposure in minority and nonminority children with asthma.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2016
    Article
  15. Article
  16. Article
  17. Article
  18. Unexpected benefits: pathways from smoking restrictions in the home to psychological well-being and distress among urban Black and Puerto Rican Americans.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2011
    Article
  19. Recent contributions of air- and biomarkers to the control of secondhand smoke (SHS): a review.International journal of environmental research and public health · 2011
    Review
  20. White blood cell DNA adducts in a cohort of asthmatic children exposed to environmental tobacco smoke.International archives of occupational and environmental health · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephen E WilsonDivision of General Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA. Stephen.Wilson@uc.edu
Robert S Kahn
Jane Khoury
Bruce P Lanphear

Funding

A RANDOMIZED TRIAL TO REDUCE ETS IN CHILDREN WITH ASTHMAR01HL065731 · NHLBI · CHILDREN'S HOSPITAL MED CTR (CINCINNATI) · PI LANPHEAR, BRUCE P · 2000 to 2003
$1.9M
Poverty, Maternal Health &Disparities in Child OutcomesK23HD040362 · NICHD · CHILDREN'S HOSPITAL MED CTR (CINCINNATI) · PI KAHN, ROBERT S · 2001 to 2005
$623k
GRANTS FOR GRADUATE TRAINING IN FAMILY MEDICINED15PE010027 · PE · VALLEY MEDICAL CENTER · PI DISTELHORST, JAMES S · 1986 to 1990
–
BHP HRSA HHS T32PE10027NHLBI NIH HHS R01 HL65731NICHD NIH HHS K23 HD40362
6 · The paper itself

Abstract

Exposure to environmental tobacco smoke (ETS) is a major cause of morbidity and mortality among U.S. children. Despite African-American children's having a lower reported exposure to tobacco compared to whites, they suffer disproportionately from tobacco-related illnesses and have higher levels of serum cotinine than white children. The goal of this study was to test whether African-American children have higher levels of serum and hair cotinine, after accounting for ETS exposure and various housing characteristics. We investigated the level of cotinine in both hair and serum in a sample of 222 children with asthma. Using a previously validated survey for adult smokers, we assessed each child's exposure to ETS. We collected detailed information on the primary residence, including home volume, ventilation, and overall home configuration. Despite a lower reported ETS exposure, African-American children had higher mean levels of serum cotinine (1.41 ng/mL vs. 0.97 ng/mL; p = 0.03) and hair cotinine (0.25 ng/mg vs. 0.07 ng/mg; p < 0.001) compared with white children. After adjusting for ETS exposure, housing size, and other demographic characteristics, serum and hair cotinine levels remained significantly higher in African-American children (ss = 0.34, p = 0.03) than in white children (ss = 1.06, p < 0.001). Housing volume was significantly associated with both serum and hair cotinine but did not fully explain the race difference. Our results demonstrate that, despite a lower reported exposure to ETS, African-American children with asthma had significantly higher levels of both serum and hair cotinine than did white children. Identifying causes and consequences of increased cotinine may help explain the striking differences in tobacco-related illnesses.

Indexed as

Black PeopleWhite PeopleAsthmaBlack or African AmericanChildCotinineDouble-Blind MethodFemaleHairHousingHumansMalePlacebosRisk AssessmentTobacco Smoke PollutionVentilationCotininePlacebosTobacco Smoke Pollution

Identifiers

PMID15743729
PMCPMC1253766

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.