ArticleEnvironmental health perspectives2005
Children's exposure to volatile organic compounds as determined by longitudinal measurements in blood.
Article in Environmental health perspectives, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Indoor Air Pollution and the Health of Vulnerable Groups: A Systematic Review Focused on Particulate Matter (PM), Volatile Organic Compounds (VOCs) and Their Effects on Children and People with Pre-Existing Lung Disease.International journal of environmental research and public health · 2022Pooled it
- Re-assessment of the risks to public health related to the genotoxicity of styrene present in plastic food contact materials.EFSA journal. European Food Safety Authority · 2025Article
- Article
- Autophagy dysregulation in trichloroethene-mediated inflammation and autoimmune response.Toxicology · 2023Article
- Profile of Environmental Chemicals in the Korean Population-Results of the Korean National Environmental Health Survey (KoNEHS) Cycle 3, 2015-2017.International journal of environmental research and public health · 2022Article
- Determinants of environmental styrene exposure in Gulf coast residents.Journal of exposure science & environmental epidemiology · 2019Article
- Colorimetric Gas Sensing Washable Threads for Smart Textiles.Scientific reports · 2019Article
- Predictors of blood volatile organic compound levels in Gulf coast residents.Journal of exposure science & environmental epidemiology · 2018Article
- Assessment of Exposure to VOCs among Pregnant Women in the National Children's Study.International journal of environmental research and public health · 2016Article
- Comparison of blood volatile organic compound levels in residents of Calcasieu and Lafayette Parishes, LA, with US reference ranges.Journal of exposure science & environmental epidemiology · 2014Article
- Metabolic changes and DNA hypomethylation in cerebellum are associated with behavioral alterations in mice exposed to trichloroethylene postnatally.Toxicology and applied pharmacology · 2013Article
- Blood and breath levels of selected volatile organic compounds in healthy volunteers.The Analyst · 2013Article
- The use of biomonitoring data in exposure and human health risk assessment: benzene case study.Critical reviews in toxicology · 2013Review
- Postnatal exposure to trichloroethylene alters glutathione redox homeostasis, methylation potential, and neurotrophin expression in the mouse hippocampus.Neurotoxicology · 2012Article
- Interpreting variability in population biomonitoring data: role of elimination kinetics.Journal of exposure science & environmental epidemiology · 2012Article
- Trends of VOC exposures among a nationally representative sample: Analysis of the NHANES 1988 through 2004 data sets.Atmospheric environment (Oxford, England : 1994) · 2011Article
- Relationships between levels of volatile organic compounds in air and blood from the general population.Journal of exposure science & environmental epidemiology · 2008Article
- Current state of the science: health effects and indoor environmental quality.Environmental health perspectives · 2007Review
- Assessing cumulative health risks from exposure to environmental mixtures - three fundamental questions.Environmental health perspectives · 2007Article
- Volatile organic compounds and pulmonary function in the Third National Health and Nutrition Examination Survey, 1988-1994.Environmental health perspectives · 2006Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood concentrations of 11 volatile organic compounds (VOCs) were measured up to four times over 2 years in a probability sample of more than 150 children from two poor, minority neighborhoods in Minneapolis, Minnesota. Blood levels of benzene, carbon tetrachloride, trichloroethene, and m-/p-xylene were comparable with those measured in selected adults from the Third National Health and Nutrition Examination Survey (NHANES III), whereas concentrations of ethylbenzene, tetrachloroethylene, toluene, 1,1,1-trichloroethane, and o-xylene were two or more times lower in the children. Blood levels of styrene were more than twice as high, and for about 10% of the children 1,4-dichlorobenzene levels were greater than or equal to 10 times higher compared with NHANES III subjects. We observed strong statistical associations between numerous pairwise combinations of individual VOCs in blood (e.g., benzene and m-/p-xylene, m-/p-xylene and o-xylene, 1,1,1-trichloroethane and m-/p-xylene, and 1,1,1-trichloroethane and trichloroethene). Between-child variability was higher than within-child variability for 1,4-dichlorobenzene and tetrachloroethylene. Between- and within-child variability were approximately the same for ethylbenzene and 1,1,1-trichloroethane, and between-child was lower than within-child variability for the other seven compounds. Two-day, integrated personal air measurements explained almost 79% of the variance in blood levels for 1,4-dichlorobenzene and approximately 20% for tetrachloroethylene, toluene, m-/p-xylene, and o-xylene. Personal air measurements explained much less of the variance (between 0.5 and 8%) for trichloroethene, styrene, benzene, and ethylbenzene. We observed no significant statistical associations between total urinary cotinine (a biomarker for exposure to environmental tobacco smoke) and blood VOC concentrations. For siblings living in the same household, we found strong statistical associations between measured blood VOC concentrations.
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