ArticleMedical & biological engineering & computing2005
In vitro validation of some flow assumptions for the prediction of the pressure distribution during obstructive sleep apnoea.
Article in Medical & biological engineering & computing, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The Biomechanical Mechanism of Upper Airway Collapse in OSAHS Patients Using Clinical Monitoring Data during Natural Sleep.Sensors (Basel, Switzerland) · 2021Article
- Numerical and Experimental Analysis of Inhalation Airflow Dynamics in a Human Pharyngeal Airway.International journal of environmental research and public health · 2020Article
- Three-dimensional Evaluation of Nasal Surgery in Patients with Obstructive Sleep Apnea.Chinese medical journal · 2016Article
- An observational cohort study of the effects of septoplasty with or without inferior turbinate reduction in patients with obstructive sleep apnea.BMC ear, nose, and throat disorders · 2014Article
- Experimental validation of quasi-one-dimensional and two-dimensional steady glottal flow models.Medical & biological engineering & computing · 2010Article
- Modelling the human pharyngeal airway: validation of numerical simulations using in vitro experiments.Medical & biological engineering & computing · 2009Article
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Authors and funding
3 authors.
Funding
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Abstract
An adequate description of the pressure distribution exerted by the fluid flow on pharyngeal walls is a first requirement to enhance the understanding, modelling and, consequently, the prediction of airway collapse during obstructive sleep apnoea. From a fluid mechanical point of view, several flow assumptions can be formulated to reduce the governing flow equations. The relevance of some major flow assumptions and the accuracy of the resulting flow description with respect to obstructive sleep apnoea was investigated on a rigid geometrical replica of the pharynx. Special attention was given to the influence of geometrical asymmetry and to the position of the flow separation point. An in vitro experimental and theoretical study of steady pharyngeal fluid flow is presented for different constriction heights and upstream pressures. Pressure and velocity distributions along a rigid in vitro replica of the oro-pharyngeal cavity were compared with different flow predictions based on various assumptions. Fluid flow models were tested for volume flow rates ranging from 5 to 120 1 min(-1) and for minimum apertures between 1.45 and 3.00 mm. Two-dimensional flow models were required and predicted experimental results with an accuracy of 15%. Flow theories classically used in the case of a Starling resistor provided poor agreement.
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