ArticlePlant physiology2005
Global transcription profiling reveals comprehensive insights into hypoxic response in Arabidopsis.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.
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Who cites it
120 citing papers in PubMed, 324 citations in OpenAlex.
- Flooding-induced transcriptomic responses and yield stability in oil palm (Elaeis guineensis).Planta · 2026Article
- The SnRK1-RAP2.4h-PIP2 module contributes to the trade-off between growth and hypoxia tolerance in plants.Nature communications · 2026Article
- Vacuum and Sonication Treatment Enable Efficient Transient Gene Expression in Various Monocot and Eudicot Plant Seedlings.ACS synthetic biology · 2026Article
- Cross-Regulation of Metabolic and Immune Pathways in Plants Under Hypoxic Conditions.Plants (Basel, Switzerland) · 2026Review
- Insights into enhanced, divergent, and additive responses to single and combined hypoxia-salt stress.BMC plant biology · 2026Article
- A synthetic ERFVII-dependent circuit in yeast sheds light on the regulation of early hypoxic responses of plants.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Determining the Critical Period of Continuous Waterlogging in Maize: An Analysis of Physiological, Biochemical, and Transcriptomic Traits.Plants (Basel, Switzerland) · 2026Article
- Translational insights into abiotic interactions: From Arabidopsis to crop plants.The Plant cell · 2025Review
- Comparative transcriptomic and proteomic analyses of hypoxia response in wild and cultivated tomato roots.BMC genomics · 2025Article
- Article
- Recent progress in understanding the cellular and genetic basis of plant responses to low oxygen holds promise for developing flood-resilient crops.Journal of experimental botany · 2024Article
- Transcriptome Analysis Reveals the Molecular Mechanism and Responsive Genes of Waterlogging Stress inInternational journal of molecular sciences · 2023Article
- Comparative transcriptomic analysis of germinating rice seedlings to individual and combined anaerobic and cold stress.BMC genomics · 2023Article
- Unraveling the mystery of canopy dieback caused by citrus disease Huanglongbing and its link to hypoxia stress.Frontiers in plant science · 2023Article
- Identification of Functional Genetic Variations Underlying Flooding Tolerance in Brazilian Soybean Genotypes.International journal of molecular sciences · 2022Article
- Meta-Analysis of RNA Sequencing Data of Arabidopsis and Rice under Hypoxia.Life (Basel, Switzerland) · 2022Article
- Overexpression of GhKTI12 Enhances Seed Yield and Biomass Production in Nicotiana Tabacum.Genes · 2022Article
- Exogenous treatment with melatonin enhances waterlogging tolerance of kiwifruit plants.Frontiers in plant science · 2022Article
- Transcriptomic profiling suggests candidate molecular responses to waterlogging in cassava.PloS one · 2022Article
- Hydrogen Sulfide Enhances Plant Tolerance to Waterlogging Stress.Plants (Basel, Switzerland) · 2021Review
60 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants have evolved adaptation mechanisms to sense oxygen deficiency in their environments and make coordinated physiological and structural adjustments to enhance their hypoxic tolerance. To gain insight into how plants respond to low-oxygen stress, gene expression profiling using whole-genome DNA amplicon microarrays was carried out at seven time points over 24 h, in wild-type and transgenic P(SAG12):ipt Arabidopsis (Arabidopsis thaliana) plants under normoxic and hypoxic conditions. Transcript levels of genes involved in glycolysis and fermentation pathways, ethylene synthesis and perception, calcium signaling, nitrogen utilization, trehalose metabolism, and alkaloid synthesis were significantly altered in response to oxygen limitation. Analysis based on gene ontology assignments suggested a significant down-regulation of genes whose functions are associated with cell walls, nucleosome structures, water channels, and ion transporters and a significant up-regulation of genes involved in transcriptional regulation, protein kinase activity, and auxin responses under conditions of oxygen shortage. Promoter analysis on a cluster of up-regulated genes revealed a significant overrepresentation of the AtMYB2-binding motif (GT motif), a sugar response element-like motif, and a G-box-related sequence, and also identified several putative anaerobic response elements. Finally, quantitative real-time polymerase chain reactions using 29 selected genes independently verified the microarray results. This study represents one of the most comprehensive analyses conducted to date investigating hypoxia-responsive transcriptional networks in plants.
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