ReviewThe Journal of physiology2005
Developmental processes and the induction of cardiovascular function: conceptual aspects.
Review in The Journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 87 citations in OpenAlex.
- Early Life Origins of Obesity and Related Complications.Indian journal of pediatrics · 2018Review
- Effects of exercise prior or during pregnancy in high fat diet fed mice alter bone gene expression of female offspring: An experimental study.International journal of reproductive biomedicine · 2017Article
- Impact of maternal cigarette smoke exposure on brain inflammation and oxidative stress in male mice offspring.Scientific reports · 2016Article
- The developmental environment, epigenetic biomarkers and long-term health.Journal of developmental origins of health and disease · 2015Review
- Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice.Sleep · 2015Article
- Mitigating or exacerbating effects of maternal-fetal programming of female mice through the food choice environment.Endocrinology · 2015Article
- From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?Clinical epigenetics · 2015Article
- Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Moderate physical training attenuates muscle-specific effects on fibre type composition in adult rats submitted to a perinatal maternal low-protein diet.European journal of nutrition · 2012Article
- Gene expression in the placenta: maternal stress and epigenetic responses.The International journal of developmental biology · 2010Review
- Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function.The Journal of physiology · 2008Article
- Molecular, cellular and endocrine signalling in the perinatal cardiovascular system: interplay and developmental programming.The Journal of physiology · 2005Article
Corrections and comments
- Commented on by
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The epidemiological basis of the developmental origins of disease concept is now widely accepted. The current impetus in research concerns establishing the underlying mechanisms. We discuss the wider biological nature of the phenomenon, with particular reference to 'maternal effects', the processes observed in many species by which the mother can induce phenotypic effects in her offspring. Animal models permit investigation of the induction of cardiovascular phenotypic attributes which resemble pathological effects in humans. We discuss the importance of transitions in aspects of the pre- versus the postnatal environment, with emphasis on nutrition and energy expenditure, and the critical role which the timing of environmental cues plays in inducing effects on the offspring. Coupled with the effects of specific maternal dietary components, the effects on the offspring are argued to involve epigenetic mechanisms. In this review we provide a conceptual framework for synthesising experimental and clinical data, important for considering the impact of the developmental origins concept in a life-course approach to the prevention of cardiovascular disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.