ArticleBritish journal of sports medicine2005
Individual variation in the erythropoietic response to altitude training in elite junior swimmers.
Article in British journal of sports medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07337928 (Altitude Training Effectiveness; Is There a Role for Sleep and Menstrual Health?), which is not on this map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Altitude Training Effectiveness; Is There a Role for Sleep and Menstrual Health?
Who cites it
40 citing papers in PubMed.
- Hypoxic re-exposure retains hematological but not performance adaptations post-altitude training.European journal of applied physiology · 2021Trial
- Dose-response relationship of intermittent normobaric hypoxia to stimulate erythropoietin in the context of health promotion in young and old people.European journal of applied physiology · 2019Trial
- Influence of altitude training modality on performance and total haemoglobin mass in elite swimmers.European journal of applied physiology · 2012Trial
- Living high-training low: effect on erythropoiesis and maximal aerobic performance in elite Nordic skiers.European journal of applied physiology · 2006Trial
- Comparison of adaptations to four weeks of continuous hypoxic training between healthy men with lower and higher initial aerobic fitness.Frontiers in physiology · 2026Article
- Haemoglobin mass responses and performance outcomes among high-performance swimmers following a 3-week live-high, train-high camp at 2320 m.European journal of applied physiology · 2024Article
- Article
- Inter-individual variability in peripheral oxygen saturation and repeated sprint performance in hypoxia: an observational study of highly-trained subjects.Frontiers in sports and active living · 2024Article
- Hematological and performance adaptations to altitude training (2,320 m) in elite middle-distance and distance swimmers.Frontiers in physiology · 2024Article
- A study of survival strategies for improving acclimatization of lowlanders at high-altitude.Heliyon · 2023Review
- Relationships between Changes in Hematological Adaptations and Exercise Capacity in Olympic Rowers after a Period of Reduced Training Loads.Journal of human kinetics · 2023Article
- Effect of hypobaric hypoxia on hematological parameters related to oxygen transport, blood volume and oxygen consumption in adolescent endurance-training athletes.Journal of exercise science and fitness · 2022Article
- Primum non nocere; It's time to consider altitude training as the medical intervention it actually is!Frontiers in psychology · 2022Review
- Dietary Nitrate Supplementation Is Not Helpful for Endurance Performance at Simulated Altitude Even When Combined With Intermittent Normobaric Hypoxic Training.Frontiers in physiology · 2022Article
- Impact of Pharmacologically Left Shifting the Oxygen-Hemoglobin Dissociation Curve on Arterial Blood Gases and Pulmonary Gas Exchange During Maximal Exercise in Hypoxia.High altitude medicine & biology · 2021Article
- Swimming turn performance: the distinguishing factor in 1500 m world championship freestyle races?BMC research notes · 2021Article
- Causes and Consequences of Interindividual Response Variability: A Call to Apply a More Rigorous Research Design in Acute Exercise-Cognition Studies.Frontiers in physiology · 2021Article
- Effects of Sprint Interval Training at Different Altitudes on Cycling Performance at Sea-Level.Sports (Basel, Switzerland) · 2020Article
- Effects of an allosteric hemoglobin affinity modulator on arterial blood gases and cardiopulmonary responses during normoxic and hypoxic low-intensity exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- The effect of intermittent hypoxic exposure on erythropoietic response and hematological variables in elite athletes.Physiological research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesInter-individual variations in sea level performance after altitude training have been attributed, at least in part, to an inter-individual variability in hypoxia induced erythropoiesis. The aim of the present study was to examine whether the variability in the increase in total haemoglobin mass after training at moderate altitude could be predicted by the erythropoietin response after 4 h exposure to normobaric hypoxia at an ambient Po(2) corresponding to the training altitude.
methodsErythropoietin levels were measured in 16 elite junior swimmers before and after 4 h exposure to normobaric hypoxia (Fio(2) 0.15, approximately 2500 m) as well as repeatedly during 3 week altitude training (2100-2300 m). Before and after the altitude training, total haemoglobin mass (CO rebreathing) and performance in a stepwise increasing swimming test were determined.
resultsThe erythropoietin increase (10-185%) after 4 h exposure to normobaric hypoxia showed considerable inter-individual variation and was significantly (p<0.001) correlated with the acute erythropoietin increase during altitude training but not with the change in total haemoglobin mass (significant increase of approximately 6% on average). The change in sea level performance after altitude training was not related to the change in total haemoglobin mass.
conclusionsThe results of the present prospective study confirmed the wide inter-individual variability in erythropoietic response to altitude training in elite athletes. However, their erythropoietin response to acute altitude exposure might not identify those athletes who respond to altitude training with an increase in total haemoglobin mass.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.