ArticleThe Journal of experimental medicine2005
Selecting B cells and plasma cells to memory.
Article in The Journal of experimental medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 46 citations in OpenAlex.
- Differences in mouse and human nonmemory B cell pools.Journal of immunology (Baltimore, Md. : 1950) · 2014Trial
- Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus.Arthritis research & therapy · 2006Trial
- Innate immunity and training to subvert original antigenic sin by the humoral immune response.eLife · 2025Article
- Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium.PLoS medicine · 2009Article
- Phenotypic and functional heterogeneity of human memory B cells.Seminars in immunology · 2008Review
- The kinetics and phenotype of the human B-cell response following immunization with a heptavalent pneumococcal-CRM conjugate vaccine.Immunology · 2006Article
- Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow.The Journal of experimental medicine · 2005Article
- Manipulating B cell homeostasis: a key component in the advancement of targeted strategies.Archivum immunologiae et therapiae experimentalisReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humoral immunity appears to be based on immunological memory provided by memory plasma cells, which secrete protective antibodies, and memory B cells, which react to antigen challenge by differentiating into plasma cells. How these differentiation pathways relate to each other, how cells are selected into these memory populations, and how these populations are maintained remains enigmatic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.