ReviewArchives of disease in childhood. Fetal and neonatal edition2005
Vitamin A and preterm infants: what we know, what we don't know, and what we need to know.
Review in Archives of disease in childhood. Fetal and neonatal edition, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 5 syntheses or guidelines pooled it, 155 citations in OpenAlex.
- Pooled it
- Oral vitamin A supplementation in preterm infants to improve health outcomes: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Pooled it
- Early neonatal vitamin A supplementation and infant mortality: an individual participant data meta-analysis of randomised controlled trials.Archives of disease in childhood · 2019Pooled it
- Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants.The Cochrane database of systematic reviews · 2016Pooled it
- Should Vitamin A Injections to Prevent Bronchopulmonary Dysplasia or Death Be Reserved for High-Risk Infants? Reanalysis of the National Institute of Child Health and Human Development Neonatal Research Network Randomized Trial.The Journal of pediatrics · 2021Trial
- EARLY VITAMIN A SUPPLEMENTATION IMPROVES THE OUTCOME OF RETINOPATHY OF PREMATURITY IN EXTREMELY PRETERM INFANTS.Retina (Philadelphia, Pa.) · 2020Trial
- Oral vitamin A supplementation in very low birth weight neonates: a randomized controlled trial.European journal of pediatrics · 2019Trial
- Effects of early inhaled nitric oxide therapy and vitamin A supplementation on the risk for bronchopulmonary dysplasia in premature newborns with respiratory failure.The Journal of pediatrics · 2014Trial
- A double-blind, randomized clinical trial of the effect of omega-3 fatty acids on the oxidative stress of preterm neonates fed through parenteral nutrition.European journal of clinical nutrition · 2010Trial
- Comparison of two types of TPN prescription methods in preterm neonates.Pharmacy world & science : PWS · 2009Trial
- Inhaled vitamin A mitigates hyperoxia-induced acute and chronic lung damage in a neonatal rat model of bronchopulmonary dysplasia.American journal of respiratory cell and molecular biology · 2026Article
- Article
- Take a deep breath: the important role of vitamin A in neonatal lung development and visiting the potential of aerosolized delivery for bronchopulmonary dysplasia prevention.Expert review of respiratory medicine · 2026Article
- Efficacy comparison of 21 interventions to prevent retinopathy of prematurity: a Bayesian network meta-analysis of randomized controlled trials.Eye (London, England) · 2024Article
- Improving growth in preterm infants through nutrition: a practical overview.Frontiers in nutrition · 2024Review
- Dilemmas in human milk fortification.Journal of perinatology : official journal of the California Perinatal Association · 2023Review
- Review
- Association of lower vitamin a levels in neonates and their mothers with increased risk of neonatal late-onset sepsis: A case-control study.Journal of mother and child · 2022Article
- The Role of Nutrition in the Prevention and Management of Bronchopulmonary Dysplasia: A Literature Review and Clinical Approach.International journal of environmental research and public health · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin A is essential for optimal growth and development. In the developing world, vitamin A supplementation of the newborn infant reduces mortality. In the developed world, extremely preterm infants are born with low body stores of vitamin A and are at high risk of vitamin A deficiency. Optimal vitamin A supplementation for this population is not clearly defined, however, and, despite evidence of benefit, early vitamin A supplementation of extremely preterm infants is not uniformly practised in the United Kingdom. There is an urgent need for studies in preterm infants that include quantification of hepatic stores and functional assessment of vitamin A status as well as long term outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.