ArticleThe Plant cell2005
Role of beta-oxidation in jasmonate biosynthesis and systemic wound signaling in tomato.
Article in The Plant cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.
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Who cites it
113 citing papers in PubMed, 303 citations in OpenAlex.
- Transcending the jasmonate-mediated growth-defense trade-off: Pathways to unlocking plant potential.Plant communications · 2026Review
- VDAL enhances wheat resistance to Fusarium graminearum by modulating defense signaling and reducing deoxynivalenol accumulation.BMC genomics · 2026Article
- Revisiting volatile organic compounds' role in plant communication using real-time bioimaging.Frontiers in plant science · 2026Article
- Transcriptional reprogramming under drought reveals divergent adaptive strategies in Quinoa.BMC plant biology · 2025Article
- 'Bud to fruit'-hormonal interactions governing early fruit development.Journal of experimental botany · 2025Review
- EcoFoldDB: Protein Structure-Guided Functional Profiling of Ecologically Relevant Microbial Traits at the Metagenome Scale.Environmental microbiology · 2025Article
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- Plant oxylipins: adaptation to environmental stresses and impact on mycotoxin contamination.Frontiers in plant science · 2025Review
- Recent Progress Regarding Jasmonates in Tea Plants: Biosynthesis, Signaling, and Function in Stress Responses.International journal of molecular sciences · 2024Review
- Jasmonate: A Hormone of Primary Importance for Temperature Stress Response in Plants.Plants (Basel, Switzerland) · 2023Review
- Probing the effects of streptomycin on Brassica napus germination and assessing its molecular interactions using extensive molecular dynamics (MD) simulations.Scientific reports · 2023Article
- Article
- Plant Peroxisome-Targeting Effector MoPtep1 Is Required for the Virulence ofInternational journal of molecular sciences · 2022Article
- Differential modulation of the lipoxygenase cascade during typical and latent Pectobacterium atrosepticum infections.Annals of botany · 2022Article
- Low Salicylic Acid Level Improves Pollen Development Under Long-Term Mild Heat Conditions in Tomato.Frontiers in plant science · 2022Article
- Disclosure of salicylic acid and jasmonic acid-responsive genes provides a molecular tool for deciphering stress responses in soybean.Scientific reports · 2021Article
- Overexpressing the N-terminus of CATALASE2 enhances plant jasmonic acid biosynthesis and resistance to necrotrophic pathogen Botrytis cinerea B05.10.Molecular plant pathology · 2021Article
- Systemic Expression of Genes Involved in the Plant Defense Response Induced by Wounding inInternational journal of molecular sciences · 2021Article
- Fungal Jasmonate as a Novel Morphogenetic Signal for Pathogenesis.Journal of fungi (Basel, Switzerland) · 2021Article
- Citric Acid-Mediated Abiotic Stress Tolerance in Plants.International journal of molecular sciences · 2021Review
53 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
Jasmonic acid (JA) is a lipid-derived signal that regulates plant defense responses to biotic stress. Here, we report the characterization of a JA-deficient mutant of tomato (Lycopersicon esculentum) that lacks local and systemic expression of defensive proteinase inhibitors (PIs) in response to wounding. Map-based cloning studies demonstrated that this phenotype results from loss of function of an acyl-CoA oxidase (ACX1A) that catalyzes the first step in the peroxisomal beta-oxidation stage of JA biosynthesis. Recombinant ACX1A exhibited a preference for C12 and C14 straight-chain acyl-CoAs and also was active in the metabolism of C18 cyclopentanoid-CoA precursors of JA. The overall growth, development, and reproduction of acx1 plants were similar to wild-type plants. However, the mutant was compromised in its defense against tobacco hornworm (Manduca sexta) attack. Grafting experiments showed that loss of ACX1A function disrupts the production of the transmissible signal for wound-induced PI expression but does not affect the recognition of this signal in undamaged responding leaves. We conclude that ACX1A is essential for the beta-oxidation stage of JA biosynthesis and that JA or its derivatives is required both for antiherbivore resistance and the production of the systemic wound signal. These findings support a role for peroxisomes in the production of lipid-based signaling molecules that promote systemic defense responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.