Evidence map›Paper›PMID 15722016›Full record

ReviewCurrent opinion in biotechnology2005

Metal-enhanced fluorescence: an emerging tool in biotechnology.

Kadir Aslan, Ignacy Gryczynski, Joanna Malicka, Evgenia Matveeva, Joseph R Lakowicz, Chris D Geddes

Abstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed.

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  19. Bi-coloured enhanced luminescence imaging by targeted switch on/off laser MEF coupling for synthetic biosensing of nanostructured human serum albumin.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  20. Review

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kadir AslanLaboratory for Advanced Medical Plasmonics, Medical Biotechnology Center, University of Maryland Biotechnology Institute, 725 West Lombard Street, Baltimore, MD 21201, USA.
Ignacy Gryczynski
Joanna Malicka
Evgenia Matveeva
Joseph R Lakowicz
Chris D Geddes

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
Fluorophore-Metallic Colloid Conjugates for Medical ImagR33EB001690 · NIBIB · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI GRYCZYNSKI, ZYGMUNT · 2005 to 2006
$304k
Metal-Enhanced Fluorescence RNA SensingR21GM070929 · NIGMS · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI GEDDES, CHRISTOPHER DARREN · 2004 to 2005
$238k
Fluorophore-Metallic Colloid Conjugates for Medical ImagR21EB001690 · NIBIB · UNIVERSITY OF MARYLAND BALTIMORE · PI GRYCZYNSKI, ZYGMUNT · 2003 to 2003
$121k
NCRR NIH HHS P41 RR008119NCRR NIH HHS RR-08119NIBIB NIH HHS R21 EB001690NIBIB NIH HHS R33 EB001690NIGMS NIH HHS R21 GM070929NIGMS NIH HHS R21GM070929
6 · The paper itself

Abstract

Over the past 15 years, fluorescence has become the dominant detection/sensing technology in medical diagnostics and biotechnology. Although fluorescence is a highly sensitive technique, where single molecules can readily be detected, there is still a drive for reduced detection limits. The detection of a fluorophore is usually limited by its quantum yield, autofluorescence of the samples and/or the photostability of the fluorophores; however, there has been a recent explosion in the use of metallic nanostructures to favorably modify the spectral properties of fluorophores and to alleviate some of these fluorophore photophysical constraints. The use of fluorophore-metal interactions has been termed radiative decay engineering, metal-enhanced fluorescence or surface-enhanced fluorescence.

Indexed as

Fluorescent DyesMetalsBiotechnologyIn Situ Hybridization, FluorescenceMicroscopy, FluorescenceNanotubesSpectrometry, FluorescenceSurface Plasmon ResonanceTechnology Assessment, BiomedicalFluorescent DyesMetals

Identifiers

PMID15722016
PMCPMC6853068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.