ReviewNeuron2005
The ins and outs of intracellular chloride in olfactory receptor neurons.
Review in Neuron, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 17 citations in OpenAlex.
- Regulation of synaptic transmission at the photoreceptor terminal: a novel role for the cation-chloride co-transporter NKCC1.The Journal of physiology · 2013Article
- Primary culture of embryonic rat olfactory receptor neurons.In vitro cellular & developmental biology. Animal · 2012Article
- The sense of smell, its signalling pathways, and the dichotomy of cilia and microvilli in olfactory sensory cells.BMC neuroscience · 2007Review
- CNS*2007. Abstracts of the 16th Annual Computational Neuroscience Meeting, Toronto, Canada, 7-12 July 2007.BMC neuroscience · 2007Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stimulation of olfactory receptor neurons with odors culminates in opening of a ciliary Ca2+-activated Cl- channel. Because intracellular Cl- ([Cl-]i) is above electrochemical equilibrium in these cells, the result is cell depolarization that triggers action potentials that carry information to the olfactory bulb. In this issue of Neuron, Reisert and coworkers use combined pharmacological and mouse genetic approaches to show that the transporter responsible for maintaining Cl- above electrochemical equilibrium is NKCC1, a (Na+)(2Cl-)(K+) cotransporter found in other tissues, including neurons.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.