ArticlePediatric nephrology (Berlin, Germany)2005
Icodextrin re-absorption varies with age in children on automated peritoneal dialysis.
Article in Pediatric nephrology (Berlin, Germany), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Clinical practice recommendations for the care of infants with stage 5 chronic kidney disease (CKD5).Pediatric nephrology (Berlin, Germany) · 2013Guideline
- Solutions for peritoneal dialysis in children: recommendations by the European Pediatric Dialysis Working Group.Pediatric nephrology (Berlin, Germany) · 2011Guideline
- Early-Start Versus Late-Start Icodextrin for Children Receiving Chronic Peritoneal Dialysis: Findings from the International Pediatric Peritoneal Dialysis Network.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Prognostic value of high intraperitoneal pressure in patients on peritoneal dialysis.International urology and nephrology · 2025Observational
- Sodium handling in pediatric patients on maintenance dialysis.Pediatric nephrology (Berlin, Germany) · 2023Review
- Factors related to ultrafiltration volume with icodextrin dialysate use in children.Pediatric nephrology (Berlin, Germany) · 2023Article
- Impact of fill volume on ultrafiltration with icodextrin in children on chronic peritoneal dialysis.Pediatric nephrology (Berlin, Germany) · 2016Article
- Quantitative Histomorphometry of the Healthy Peritoneum.Scientific reports · 2016Article
- Optimizing peritoneal dialysis prescription for volume control: the importance of varying dwell time and dwell volume.Pediatric nephrology (Berlin, Germany) · 2014Review
- Strategies for the preservation of residual renal function in pediatric dialysis patients.Pediatric nephrology (Berlin, Germany) · 2014Review
- Peritoneal dialysis prescription in children: bedside principles for optimal practice.Pediatric nephrology (Berlin, Germany) · 2009Review
- Pathogenesis and treatment of peritoneal membrane failure.Pediatric nephrology (Berlin, Germany) · 2008Review
- Peritoneal dialysis in infants.Pediatric nephrology (Berlin, Germany) · 2006Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Information on the use of Icodextrin in children remains scarce; however, it is believed that the characteristics are similar across all ages. We report the use of Icodextrin in a cohort of pediatric automated peritoneal dialysis (APD) patients younger than those previously reported (n=8, median age of 2.8, range 0.02-17.1 years). Net Icodextrin daytime dwell ultrafiltration was calculated in each patient for every day on therapy as ml/h/m2. Half of the patients showed re-absorption even when reducing Icodextrin dwells from a median of 10 to 6 h. All four patients who re-absorbed the Icodextrin (ranging from -23.7+/-7.5 to -2.5+/-6.0 ml/h/m2) were treated with cyclic nocturnal APD, and three of these four patients were high transporters on the peritoneal equilibration test (PET). Icodextrin fluid removal correlated significantly with age (Spearman rank r=0.8571, P=0.0107). The data suggest that Icodextrin behaves differently in young children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.