Evidence map›Paper›PMID 15716460›Full record

ArticleJournal of bacteriology2005

Transcriptome of Treponema pallidum: gene expression profile during experimental rabbit infection.

David Smajs, Matthew McKevitt, Jerrilyn K Howell, Steven J Norris, Wei-Wen Cai, Timothy Palzkill, George M Weinstock

Abstract read
In one paragraph

Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Proteome Analysis of SevenJournal of proteome research · 2025
    Article
  2. Article
  3. B-Cell Epitope Mapping of theDiagnostics (Basel, Switzerland) · 2025
    Article
  4. In-Depth Proteome Coverage of In Vitro-CulturedJournal of proteome research · 2024
    Article
  5. Article
  6. Article
  7. Heliyon · 2022
    Article
  8. Article
  9. High-throughput nanopore sequencing ofFrontiers in microbiology · 2022
    Article
  10. Notes on syphilis vaccine development.Frontiers in immunology · 2022
    Review
  11. Article
  12. AnInfection and immunity · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Structural characterization of Treponema pallidum Tp0225 reveals an unexpected leucine-rich repeat architecture.Acta crystallographica. Section F, Structural biology communications · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David SmajsHuman Genome Sequencing Center, University of Texas-Houston Medical School, Houston, Texas, USA. dsmajs@med.muni.cz
Matthew McKevitt
Jerrilyn K Howell
Steven J Norris
Wei-Wen Cai
Timothy Palzkill
George M Weinstock

Funding

A TRIAL TO REDUCE HEPATITIS C AMONG INJECTION DRUG USERSR01DA013759 · NIDA · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI STEIN, MICHAEL D · 2000 to 2003
$1.9M
WHOLE GENOME PHAGE DISPLAY OF T PALLIDUM GENESR01AI045842 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI PALZKILL, TIMOTHY · 1999 to 2006
$1.8M
Tuning for Complex Visual Stimuli in V1R01EY013759 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAS, ANIRUDDHA · 2003 to 2006
$1.6M
Physiologic Characteristics of Treponema PallidumR01AI049252 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NORRIS, STEVEN J · 2001 to 2004
$1.3M
GENETIC ORGANIZATION OF TREPONEMA DENTICOLAR01DE012488 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WEINSTOCK, GEORGE M · 1998 to 2000
$719k
MICROBIAL GENOMICSR01DE013759 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WEINSTOCK, GEORGE M · 2000 to 2001
$706k
NEI NIH HHS R01 EY013759NIAID NIH HHS AI45842NIAID NIH HHS R01 AI045842NIAID NIH HHS R01 AI049252NIAID NIH HHS R01 AI49252NIDA NIH HHS R01 DA013759NIDCR NIH HHS R01 DE12488NIDCR NIH HHS R01 DE13759
6 · The paper itself

Abstract

RNA transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated from experimentally infected rabbits were determined by the use of DNA microarray technology. This characterization of the T. pallidum transcriptome during experimental infection provides further insight into the importance of gene expression levels for the survival and pathogenesis of this bacterium.

Indexed as

AnimalsGene ExpressionGene Expression ProfilingOligonucleotide Array Sequence AnalysisOpen Reading FramesRabbitsRNA, BacterialRNA, MessengerSyphilisTreponema pallidumRNA, BacterialRNA, Messenger

Identifiers

PMID15716460
PMCPMC1063989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.