Evidence map›Paper›PMID 15714343›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2004

Costs and consequences of botulinum toxin type A use. Management of children with cerebral palsy in Germany.

Francis J Ruiz, Julian F Guest, Almut Lehmann, Alison M Davie, Karen Güttler, Olaf Schlüter, Götz Dreiss

Abstract readComparative Study
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In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francis J RuizCatalyst Health Economics Consultants, Northwood, Middlesex, UK.
Julian F Guest
Almut Lehmann
Alison M Davie
Karen Güttler
Olaf Schlüter
Götz Dreiss

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was a retrospective survey of the management of a cohort of children with cerebral palsy at Seepark Hospital, Germany, who did (cases; n=107) and did not (controls; n=107) receive botulinum toxin injections. Data on healthcare resource use and clinical outcomes over 12 months were collected from the date cases received their first injection and from the date controls were first admitted into hospital. Botulinum toxin use led to an 85% reduction in the number of children requiring surgery. Additionally, controls used significantly more healthcare resources than cases, particularly hospital bed days (69.2+/-34.1 vs. 27.5+/-27.9 days; p <0.0001). The total cost of managing cases and controls was <euro>16,700 and <euro>33,800, respectively. In conclusion, use of botulinum toxin released resources for alternative use during the first year following treatment, without any loss of clinical improvement. However, it is unknown how botulinum toxin affected the need for surgery and associated outcomes in subsequent years.

Indexed as

AdolescentBotulinum Toxins, Type ACerebral PalsyChildChild, PreschoolCohort StudiesCosts and Cost AnalysisFemaleGermanyHealth ResourcesHumansLength of StayMaleMultivariate AnalysisNeuromuscular AgentsPatient SelectionBotulinum Toxins, Type ANeuromuscular Agents

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.