ArticleMolecular and cellular biology2005
Early expression of yeast genes affected by chemical stress.
Article in Molecular and cellular biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Transcriptional Response of Candida auris to the Mrr1 Inducers Methylglyoxal and Benomyl.mSphere · 2022Article
- Dependence of Graphene Oxide (GO) Toxicity on Oxidation Level, Elemental Composition, and Size.International journal of molecular sciences · 2021Article
- Comparative and mechanistic toxicity assessment of structure-dependent toxicity of carbon-based nanomaterials.Journal of hazardous materials · 2021Article
- Sex differences in early transcriptomic responses to oxidative stress in the copepod Tigriopus californicus.BMC genomics · 2020Article
- Assessing regulatory features of the current transcriptional network of Saccharomyces cerevisiae.Scientific reports · 2020Article
- Toxicity of Single-Walled Carbon Nanotubes (SWCNTs): Effect of Lengths, Functional Groups and Electronic Structures Revealed by a Quantitative Toxicogenomics Assay.Environmental science. Nano · 2020Article
- Cellular response upon proliferation in the presence of an active mitotic checkpoint.Life science alliance · 2019Article
- Yeast AP-1 like transcription factors (Yap) and stress response: a current overview.Microbial cell (Graz, Austria) · 2019Review
- Penetrating cations induce pleiotropic drug resistance in yeast.Scientific reports · 2018Article
- Leptin Stimulates Cellular Glycolysis Through a STAT3 Dependent Mechanism in Tilapia.Frontiers in endocrinology · 2018Article
- Endonucleolytic cleavage in the expansion segment 7 of 25S rRNA is an early marker of low-level oxidative stress in yeast.The Journal of biological chemistry · 2017Article
- Candida albicans Swi/Snf and Mediator Complexes Differentially Regulate Mrr1-InducedAntimicrobial agents and chemotherapy · 2017Article
- Yeast response and tolerance to benzoic acid involves the Gcn4- and Stp1-regulated multidrug/multixenobiotic resistance transporter Tpo1.Applied microbiology and biotechnology · 2017Article
- Induction of Candida albicans drug resistance genes by hybrid zinc cluster transcription factors.Antimicrobial agents and chemotherapy · 2015Article
- SAGA/ADA complex subunit Ada2 is required for Cap1- but not Mrr1-mediated upregulation of the Candida albicans multidrug efflux pump MDR1.Antimicrobial agents and chemotherapy · 2014Article
- Article
- Loss of cardiolipin leads to perturbation of mitochondrial and cellular iron homeostasis.The Journal of biological chemistry · 2013Article
- The genome-wide early temporal response of Saccharomyces cerevisiae to oxidative stress induced by cumene hydroperoxide.PloS one · 2013Article
- RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicans.BMC genomics · 2012Article
- Interactions between the kinetochore complex and the protein kinase A pathway in Saccharomyces cerevisiae.G3 (Bethesda, Md.) · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The variety of environmental stresses is probably the major challenge imposed on transcription activators and the transcriptional machinery. To precisely describe the very early genomic response developed by yeast to accommodate a chemical stress, we performed time course analyses of the modifications of the yeast gene expression program which immediately follows the addition of the antimitotic drug benomyl. Similar analyses were conducted with different isogenic yeast strains in which genes coding for relevant transcription factors were deleted and coupled with efficient bioinformatics tools. Yap1 and Pdr1, two well-known key mediators of stress tolerance, appeared to be responsible for the very rapid establishment of a transient transcriptional response encompassing 119 genes. Yap1, which plays a predominant role in this response, binds, in vivo, promoters of genes which are not automatically up-regulated. We proposed that Yap1 nuclear localization and DNA binding are necessary but not sufficient to elicit the specificity of the chemical stress response.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.