ArticleGut2005
The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway.
Article in Gut, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association between TLR2 and TLR4 Gene Polymorphisms and the Susceptibility to Inflammatory Bowel Disease: A Meta-Analysis.PloS one · 2015Pooled it
- Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: New data and a meta-analysis.BMC gastroenterology · 2014Pooled it
- Association between CD14 gene C-260T polymorphism and inflammatory bowel disease: a meta-analysis.PloS one · 2012Pooled it
- Escherichia coli-host macrophage interactions in the pathogenesis of inflammatory bowel disease.World journal of gastroenterology · 2014Review
- Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers.OncoTargets and therapy · 2013Review
- Readressing the role of Toll-like receptor-4 alleles in inflammatory bowel disease: colitis, smoking, and seroreactivity.Digestive diseases and sciences · 2013Article
- Toll-like receptors and human disease: lessons from single nucleotide polymorphisms.Current genomics · 2012Article
- Role of genetics in the diagnosis and prognosis of Crohn's disease.World journal of gastroenterology · 2012Review
- Role of genetics in the diagnosis and prognosis of Crohn's disease.World journal of gastroenterology · 2011Review
- The role of bacteria and pattern-recognition receptors in Crohn's disease.Nature reviews. Gastroenterology & hepatology · 2011Review
- Tolllike receptor 4 (TLR4) polymorphisms in Tunisian patients with Crohn's disease: genotype-phenotype correlation.BMC gastroenterology · 2009Article
- Clustering of (auto)immune diseases with early-onset and complicated inflammatory bowel disease.European journal of pediatrics · 2009Article
- Inflammatory bowel disease: review from the aspect of genetics.Journal of gastroenterology · 2009Review
- Inflammatory bowel disease: genetic and epidemiologic considerations.World journal of gastroenterology · 2008Review
- Review
- Novel genetic markers in inflammatory bowel disease.World journal of gastroenterology · 2007Review
- The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases.Genes and immunity · 2007Article
- Toll-like receptor (TLR) 4 polymorphism Asp299Gly is not associated with disease course in Dutch sarcoidosis patients.Clinical and experimental immunology · 2006Article
- Polymorphisms of CD14 gene and TLR4 gene are not associated with ulcerative colitis in Chinese patients.Postgraduate medical journal · 2005Article
- Functional consequences of toll-like receptor 4 polymorphisms.Molecular medicine (Cambridge, Mass.)Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.