Evidence map›Paper›PMID 15704136›Full record

ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2005

Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development.

Willis X Li

Abstract readReview
In one paragraph

Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. The IL-17 pathway intertwines with neurotrophin and TLR/IL-1R pathways since its domain shuffling origin.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Finishing the egg.Genetics · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Torso, a Drosophila receptor tyrosine kinase, plays a novel role in the larval fat body in regulating insulin signaling and body growth.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2016
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Willis X LiDepartment of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York 14642, USA. willis_li@urmc.rochester.edu

Funding

Genetic Analysis of Intracellular Signaling CrosstalkR01GM065774 · NIGMS · UNIVERSITY OF ROCHESTER · PI LI, WILLIS X · 2002 to 2006
$1.3M
Network Interaction between EGFR and TGFbeta PathwaysR01GM077046 · NIGMS · UNIVERSITY OF ROCHESTER · PI LI, WILLIS X · 2006 to 2009
$940k
NIGMS NIH HHS R01 GM065774NIGMS NIH HHS R01 GM077046NIGMS NIH HHS R01GM65774
6 · The paper itself

Abstract

The Torso receptor tyrosine kinase (RTK) is required for cell fate specification in the terminal regions (head and tail) of the early Drosophila embryo. Torso contains a split tyrosine kinase domain and belongs to the type III subgroup of the RTK superfamily that also includes the platelet-derived growth factor receptors, stem cell or steel factor receptor c-Kit proto-oncoprotein, colony-stimulating factor-1 receptor, and vascular endothelial growth factor receptor. The Torso pathway has been a model system for studying RTK signal transduction. Genetic and biochemical studies of Torso signaling have provided valuable insights into the biological functions and mechanisms of RTK signaling during early Drosophila embryogenesis.

Indexed as

AnimalsDrosophilaDrosophila ProteinsEmbryonic InductionEmbryo, NonmammalianInsect ProteinsModels, BiologicalProtein Structure, TertiaryReceptor Protein-Tyrosine KinasesRNA, MessengerSignal TransductionDrosophila ProteinsInsect ProteinsReceptor Protein-Tyrosine KinasesRNA, Messengertor protein, Drosophila

Identifiers

PMID15704136
PMCPMC3092428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.