Evidence map›Paper›PMID 15703509›Full record

ArticleEuropean journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology2005

Socio-economic status in relation to risk factors associated with cardiovascular disease, in healthy individuals from the ATTICA study.

Demosthenes B Panagiotakos, Christos Pitsavos, Yannis Manios, Evangelos Polychronopoulos, Christina A Chrysohoou, Christodoulos Stefanadis

2 registry-linked trialsAbstract read
PubMed
In one paragraph

Article in European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03329729 completedstarted 2018, after this paper: background citation

Non-interventional, Multicenter Clinical Trial to Investigate the Efficacy of Rosuvastatin in Patients With Hyperlipidemia and Other Cardiovascular Risk Factors.

Ran2018Enrolled4,700Registered outcomes3Posted comparisons0ConditionsDyslipidemias, Hyperlipidemias, Quality of Life, Risk Factor, CardiovascularArmsRosuvastatin
Open the trial in the graph
NCT02392416 completednot on this mapstarted 2015, after this paper: background citation

Non-interventional, Multicenter Clinical Study to Assess the Treatment With Atorvastatin in Patient Compliance With Hyperlipidemia and Other Cardiovascular Risk Factors

TypeobservationalSponsorElpen Pharmaceutical Co. Inc.Ran2015 to 2016Enrolled900ConditionsHypercholesterolemia, Dyslipidemia
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. Factors affecting use of preventive tests for cardiovascular risk among Greeks.International journal of environmental research and public health · 2009
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Demosthenes B PanagiotakosFirst Cardiology Department, School of Medicine, University of Athens, Athens, Greece. D.b.Panagiotakos@usa.net
Christos Pitsavos
Yannis Manios
Evangelos Polychronopoulos
Christina A Chrysohoou
Christodoulos Stefanadis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial status has been related with the prevalence and incidence of cardiovascular disease. The aim of this study is to investigate the relationships between socio-economic status (SES) and clinical and biochemical factors related to coronary heart disease, in a sample of cardiovascular disease-free men and women.

designCross-sectional survey.

methodsDuring 2001-2002, 1514 men (20-87 years old) and 1528 women (20-89 years old) from the Attica region (Greece) were randomly enrolled into the study. Trends in established and emerging cardiovascular risk factors were examined across the participants' socio-economic status. A special index was developed (years of school by annual income) and three socio-economic classes were created.

resultsAn inverse relationship was found regarding all lipids and glucose levels across the tertiles of the SES index. An inverse association was observed between body mass index, waist-to-hip ratio and SES in men, but not in women. Furthermore, compared to the lowest tertile, individuals who were classified in the highest SES tertile had lower levels of C-reactive protein, fibrinogen, homocysteine, tumour necrosis factor-alpha, interleukin-6 levels and white blood cell counts, even after adjusting for various potential confounders. Finally, a considerable proportion of men and women reported lack of health knowledge and education.

conclusionsAn inverse association between SES and factors related to cardiovascular risk exists, but the causal pathway itself requires more detailed explanation before the social status can have explanatory power.

Indexed as

Social ClassAdultAgedAged, 80 and overBiomarkersBlood GlucoseCardiovascular DiseasesCohort StudiesConfounding Factors, EpidemiologicC-Reactive ProteinCytokinesFemaleGreeceHumansHypercholesterolemiaMaleBiomarkersBlood GlucoseC-Reactive ProteinCytokines

Identifiers

PMID15703509

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.