ArticleRheumatology international2006
Anti-CENP-H antibodies in patients with Sjogren's syndrome.
Article in Rheumatology international, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjögren's disease reveals common and distinct immune activation and fibroblast-mediated inflammation.Nature communications · 2025Article
- Anti-SSA/SSB-negative primary Sjögren's syndrome showing different clinical phenotypes: a retrospective study of 934 cases.Advances in rheumatology (London, England) · 2023Article
- Not all autoantibodies are clinically relevant. Classic and novel autoantibodies in Sjögren's syndrome: A critical review.Frontiers in immunology · 2022Review
- Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay.Molecular cancer · 2013Article
- Clinical correlates of a subset of anti-CENP-A antibodies cross-reacting with FOXE3p53-62 in systemic sclerosis.Arthritis research & therapy · 2013Article
- New centromere autoantigens identified in systemic sclerosis using centromere protein microarrays.The Journal of rheumatology · 2013Article
- Potential diagnostic utility of anti-centromere antibody in primary Sjögren's syndrome in the UK.Clinical rheumatology · 2012Article
- Clinical significance and diagnostic usefulness of anti-centromere antibody in Sjögren's syndrome.Clinical rheumatology · 2012Article
- Anti-centromere antibody-seropositive Sjögren's syndrome differs from conventional subgroup in clinical and pathological study.BMC musculoskeletal disorders · 2010Article
- Primary Sjogren's syndrome with anticentromere antibodies--a clinically distinct subset.Clinical rheumatology · 2010Article
- Anticentromere antibody positive Sjögren's Syndrome: a retrospective descriptive analysis.Arthritis research & therapy · 2010Article
- Clinical and serological evaluation of a novel CENP-A peptide based ELISA.Arthritis research & therapy · 2010Article
- The value of antinuclear antibodies in primary biliary cirrhosis.Clinical and experimental medicine · 2008Article
- Serum reactivity against Borrelia burgdorferi OspA in patients with rheumatoid arthritis.Clinical and vaccine immunology : CVI · 2007Article
- Sjögren's syndrome--study of autoantigens and autoantibodies.Clinical reviews in allergy & immunology · 2007Review
- Anti-CENP-A/B reactivity in samples exhibiting the centromere HEp-2 pattern is associated with a lower frequency of interstitial lung disease in limited cutaneous systemic sclerosis patients.Journal of circulating biomarkersArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anti-centromere antibody (ACA) has been reported to be associated with Sjogren's syndrome (SS) and the clinical significance of anti-CENP-H antibody remains unknown. To determine the clinical significance of anti-CENP-H and anti-centromere antibodies in primary SS, sera from 62 patients with primary SS and 40 normal controls were examined for anti-SS-A/SS-B antibodies, ACA and anti-CENP-H antibodies, by enzyme-linked immunosorbent assay and indirect immunofluorescence (IIF), respectively. Of the 62 serum samples with primary SS, 17 were positive with ACA and anti-CENP-H antibodies. Sera from SS patients with anti-CENP-H and ACA antibodies do not contain anti-SS-A/Ro and/or anti-SS-B/La antibodies. No anti-CENP-H antibody was found in sera of normal controls. An increased frequency of ACA and anti-CENP-H antibodies was found for the first time in patients with SS. Anti-CENP-H antibodies and anti-SS-A/Ro or anti-SS-B/La antibodies are present mutually exclusive. Patients with anti-CENP-H antibodies had a lower frequency of rheumatoid factor (RF). SS can be subdivided serologically into two groups; group one with anti-SS-A/Ro and/or anti-SS-B/La antibody, group two with ACA and/or anti-CENP-H antibodies. We recommend that ACA or anti-CENP-H antibodies should be considered as one of the serological markers for SS.
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Registered trials
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