ArticleBritish journal of cancer2005
Detection of oncogenic virus genomes and gene products in lung carcinoma.
Article in British journal of cancer, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Human papillomavirus and lung cancer: an overview and a meta-analysis.Journal of cancer research and clinical oncology · 2019Pooled it
- Human papillomavirus type 16 and 18 in primary lung cancers--a meta-analysis.Carcinogenesis · 2009Pooled it
- Human Papillomavirus and Other Relevant Issues in Cervical Cancer Pathogenesis.International journal of molecular sciences · 2025Review
- Review
- Epstein-Barr Virus Infection in Lung Cancer: Insights and Perspectives.Pathogens (Basel, Switzerland) · 2022Review
- Pathogenic Role of Epstein-Barr Virus in Lung Cancers.Viruses · 2021Review
- Patients withOncology letters · 2021Article
- The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties.The Journal of biological chemistry · 2019Article
- Survey for human polyomaviruses in cancer.JCI insight · 2016Article
- Human Cytomegalovirus DNA Quantification and Gene Expression in Gliomas of Different Grades.PloS one · 2016Article
- High seroprevalence of human herpesvirus type 8 infection in males with advanced lung carcinoma.Medical microbiology and immunology · 2015Article
- Detection of Merkel cell polyomavirus with a tumour-specific signature in non-small cell lung cancer.British journal of cancer · 2013Article
- Lung cancer: epidemiology, etiology, and prevention.Clinics in chest medicine · 2011Review
- HPV in exhaled breath condensate of lung cancer patients.British journal of cancer · 2011Article
- Mouse mammary tumor virus-like gene sequences are present in lung patient specimens.Virology journal · 2011Article
- Vaccination against human papilloma virus (HPV): epidemiological evidence of HPV in non-genital cancers.Pathology oncology research : POR · 2011Review
- Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients.Infectious agents and cancer · 2010Article
- Population-based trends in lung cancer incidence in women.Seminars in oncology · 2009Review
- Mesothelioma mortality in Europe: impact of asbestos consumption and simian virus 40.Orphanet journal of rare diseases · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated a series of 122 cases of small cell lung carcinomas and non-small cell lung carcinomas for the presence of several viruses that are known to be oncogenic in humans. Thus, viral genomes (DNA) and/or RNA transcripts and/or proteins of human papillomaviruses (HPV) 16, 18, 31, 33, 51, Epstein-Barr virus (EBV), human herpesvirus 8 (HHV-8), human cytomegalovirus (HCMV) and simian virus 40 (SV40) were investigated on tissue sections (prepared in tissue microarrays) with different techniques of immunohistochemistry and in situ hybridisation. None of the cases displayed a single positive tumour cell for all the viruses tested whatever the technique applied. Of note, in five cases of tumours with lymphoid infiltrates, we detected scattered EBV (EBER)-positive bystander lymphocytes. In three cases, a faint nuclear staining was found with the anti-latent nuclear antigen/LANA1 (HHV-8) antibody. These cases were checked by PCR with two sets of primers (orf 26 and orf 75) and remained negative for this latter virus. Taken together, our data strongly suggest that the conventional human oncogenic viruses (HPV, EBV, HCMV, HHV-8 and SV40) are unlikely to play some role in the development of lung carcinomas..
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.