Evidence map›Paper›PMID 15699436›Full record

ArticleClinical and diagnostic laboratory immunology2005

Relationship between intracranial granulomas and cerebrospinal fluid levels of gamma interferon and interleukin-10 in patients with tuberculous meningitis.

Adel M Mansour, Robert W Frenck, Toni Darville, Isabelle A Nakhla, Thomas F Wierzba, Yehia Sultan, Magdy I Bassiouny, Kathryn McCarthy, Richard F Jacobs

Open access · diamondAbstract read
In one paragraph

Article in Clinical and diagnostic laboratory immunology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Serum and CSF cytokines and matrix metalloproteinases in spinal tuberculosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2015
    Article
  5. Pathogenesis and immune response in tuberculous meningitis.The Malaysian journal of medical sciences : MJMS · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Adel M MansourUniversity of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Robert W Frenck
Toni Darville
Isabelle A Nakhla
Thomas F Wierzba
Yehia Sultan
Magdy I Bassiouny
Kathryn McCarthy
Richard F Jacobs
Naval Medical Research Unit Six · PEUniversity of Arkansas for Medical Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebrospinal fluid gamma interferon (IFN-gamma) and interleukin-10 levels in 39 patients with tuberculous meningitis were serially measured. Cytokine levels did not predict intracranial granuloma (IG) development, but IFN-gamma levels in the top quartile after 1 month of therapy were highly associated (odds ratio = 18) with detection of an IG by computed tomography scanning.

Indexed as

AdolescentAdultFemaleGranulomaHumansInterferon-gammaInterleukin-10MalePrognosisTuberculoma, IntracranialTuberculosis, MeningealInterferon-gammaInterleukin-10

Identifiers

PMID15699436
PMCPMC549309
OpenAlexW2123361122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.