ArticleJournal of molecular evolution2005
Diversification and independent evolution of troponin C genes in insects.
Article in Journal of molecular evolution, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Fine-tuning striated muscle performance: conserved sarcomere-level mechanisms across insect and vertebrate systems.Frontiers in physiology · 2026Review
- Evolution of Flight Muscle Contractility and Energetic Efficiency.Frontiers in physiology · 2020Review
- Invertebrate troponin: Insights into the evolution and regulation of striated muscle contraction.Archives of biochemistry and biophysics · 2019Review
- Malaria vectors in the Democratic Republic of the Congo: the mechanisms that confer insecticide resistance in Anopheles gambiae and Anopheles funestus.Malaria journal · 2017Article
- Functional redundancy and nonredundancy between two Troponin C isoforms inMolecular biology of the cell · 2017Article
- Roles of the troponin isoforms during indirect flight muscle development in Drosophila.Journal of genetics · 2014Article
- Regulating the contraction of insect flight muscle.Journal of muscle research and cell motility · 2011Review
- Structure, function and evolution of insect flight muscle.Biophysics (Nagoya-shi, Japan) · 2011Review
- Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster.BMC genomics · 2007Article
- Article
- The structural role of high molecular weight tropomyosins in dipteran indirect flight muscle and the effect of phosphorylation.Journal of muscle research and cell motility · 2006Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Troponin C (TpnC), the calcium-binding subunit of the troponin regulatory complex in the muscle thin filament, is encoded by multiple genes in insects. To understand how TpnC genes have evolved, we characterized the gene number and structure in a number of insect species. The TpnC gene complement is five genes in Drosophilidae as previously reported for D. melanogaster. Gene structures are almost identical in D. pseudoobscura, D. suboboscura, and D. virilis. Developmental patterns of expression are also conserved in Drosophila subobscura and D. virilis. Similar, but not completely equivalent, TpnC gene repertoires have been identified in the Anopheles gambiae and Apis mellifera genomes. Insect TpnC sequences can be divided into three groups, allowing a systematic classification of newly identified genes. The pattern of expression of the Apis mellifera genes essentially agrees with the pattern in Drosophilidae, providing further functional support to the classification. A model for the evolution of the TpnC genes is proposed including the most likely pathway of insect TpnC diversification. Our results suggest that the rapid increase in number and sequence specialization of the adult Type III isoforms can be correlated with the evolution of the holometabolous mode of development and the acquisition of asynchronous indirect flight muscle function in insects. This evolutionarily specialization has probably been achieved independently in different insect orders.
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