ArticleImmunogenetics2005
Interchromosomal duplication of major histocompatibility complex class I regions in rainbow trout (Oncorhynchus mykiss), a species with a presumably recent tetraploid ancestry.
Article in Immunogenetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- An Ancestral Major Histocompatibility Complex Organization in Cartilaginous Fish: Reconstructing MHC Origin and Evolution.Molecular biology and evolution · 2023Article
- Analysis of microbiota-host communication mediated by butyrate in Atlantic salmon.Computational and structural biotechnology journal · 2023Article
- Intra-specific copy number variation of MHC class II genes in the Siamese fighting fish.Immunogenetics · 2022Article
- MHC class I evolution; from Northern pike to salmonids.BMC ecology and evolution · 2021Article
- Major Histocompatibility Complex in Osteichthyes.Journal of veterinary research · 2020Article
- An Illumina approach to MHC typing of Atlantic salmon.Immunogenetics · 2020Review
- Distribution of ancient α1 and α2 domain lineages between two classical MHC class I genes and their alleles in grass carp.Immunogenetics · 2019Article
- Review
- Comparative MHC nomenclature: report from the ISAG/IUIS-VIC committee 2018.Immunogenetics · 2018Article
- Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules.BMC evolutionary biology · 2018Article
- MHC and Evolution in Teleosts.Biology · 2016Review
- A comprehensive analysis of teleost MHC class I sequences.BMC evolutionary biology · 2015Article
- Article
- Selection and phylogenetics of salmonid MHC class I: wild brown trout (Salmo trutta) differ from a non-native introduced strain.PloS one · 2013Article
- Isolation and molecular characterization of Rem2 isoforms in the rainbow trout (Oncorhynchus mykiss): Tissue and central nervous system expression.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology · 2012Article
- Primordial linkage of β2-microglobulin to the MHC.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Evolution of duplicated IgH loci in Atlantic salmon, Salmo salar.BMC genomics · 2010Article
- Article
- Comprehensive analysis of MHC class I genes from the U-, S-, and Z-lineages in Atlantic salmon.BMC genomics · 2010Article
- Comparative genomic analysis of the major histocompatibility complex class I region in the teleost genus Oryzias.Immunogenetics · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salmonid fishes are among the few animal taxa with a probable recent tetraploid ancestor. The present study is the first to compare large (>100 kb) duplicated genomic sequence fragments in such species. Two contiguous stretches with major histocompatibility complex (MHC) class I genes were detected in a rainbow trout BAC library, mapped and sequenced. The MHC class I duplicated regions, mapped by fluorescence in situ hybridization (FISH), were shown to be located on different metaphase chromosomes, Chr 14 and 18. Gene organization in both duplications is similar to that in other fishes, in that the class I loci are tightly linked with the PSMB8, PSMB9, PSMB10 and ABCB3 genes. Whereas one region, Onmy-IA, has a classical MHC class I locus (UBA), Onmy-IB encodes only non-classical class Ib proteins. The nucleotide diversity between the Onmy-IA and Onmy-IB noncoding regions is about 14%. This suggests that the MHC class I duplication event has occurred about 60 mya close to the time of an hypothesized ancestral tetraploid event. The present article is the first convincing report on the co-existence of two closely related MHC class I core regions on two different chromosomes. The interchromosomal duplication and the homology levels are supportive of the tetraploid model.
Indexed as
Identifiers
15696305What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.