ArticleCurrent microbiology2005
Subcellular location of the soluble lytic transglycosylase homologue in Staphylococcus aureus.
Article in Current microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
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- Proteomic and metabolomic responses of priority bacterial pathogens to subinhibitory concentration of antibiotics.npj antimicrobials and resistance · 2025Article
- Staphylococcus aureus cell wall maintenance - the multifaceted roles of peptidoglycan hydrolases in bacterial growth, fitness, and virulence.FEMS microbiology reviews · 2022Review
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- AViruses · 2020Article
- Roles of lytic transglycosylases in biofilm formation and β-lactam resistance in methicillin-resistantAntimicrobial agents and chemotherapy · 2019Article
- Distinct virulent network between healthcare- and community-associatedClinical proteomics · 2018Article
- Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal antibody-based probe.Virulence · 2018Article
- Differential epitope recognition in the immunodominant staphylococcal antigen A of Staphylococcus aureus by mouse versus human IgG antibodies.Scientific reports · 2017Article
- Enhancement of the pathogenicity of Staphylococcus aureus strain Newman by a small noncoding RNA SprX1.Medical microbiology and immunology · 2016Article
- Proteome Analyses ofClinical microbiology (Los Angeles, Calif.) · 2015Article
- Dormant cells of Staphylococcus aureus are resuscitated by spent culture supernatant.PloS one · 2014Article
- Bacterial cell-wall recycling.Annals of the New York Academy of Sciences · 2013Review
- Complete genome and transcriptomes of Streptococcus parasanguinis FW213: phylogenic relations and potential virulence mechanisms.PloS one · 2012Article
- Article
- Functional antibodies targeting IsaA of Staphylococcus aureus augment host immune response and open new perspectives for antibacterial therapy.Antimicrobial agents and chemotherapy · 2011Article
- Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics.PloS one · 2010Article
- Article
- Characterization of IsaA and SceD, two putative lytic transglycosylases of Staphylococcus aureus.Journal of bacteriology · 2007Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The immunodominant antigen A, IsaA, of Staphylococcus aureus was found to include a putative soluble lytic transglycosylase domain in its C-terminal region. Since the presence of this distinctive domain suggested that the protein might participate in peptidoglycan turnover, as indicated in Gram-negative bacteria, its cellular location was investigated. The protein was found not only in the culture supernatant but also in the cell wall fraction. To estimate its physiological role for the bacterium, its cell surface distribution was studied by immunoelectron microscopy. Protein A-gold particles binding to the immune complex were mainly located on the septal region of the bacterial cell surface. These data suggested that IsaA might be involved in bacterial cell separation through a preferential interaction with peptidoglycan chain.
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