ArticleJournal of clinical microbiology2005
Multiple genetically distinct groups revealed among clinical isolates identified as atypical Aspergillus fumigatus.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Fungal Nomenclature: Managing Change is the Name of the Game.Open forum infectious diseases · 2023Review
- Genomic and Phenotypic Heterogeneity of Clinical Isolates of the Human PathogensFrontiers in genetics · 2020Article
- Draft Genome Sequence of Azole-Resistant Aspergillus thermomutatus (Neosartorya pseudofischeri) Strain HMR-AF-39, Isolated from a Human Nasal Septum Abscess Aspirate.Microbiology resource announcements · 2019Article
- Draft Genome Sequences of Azole-Resistant and Azole-Susceptible Aspergillus turcosus Clinical Isolates Recovered from Bronchoalveolar Lavage Fluid Samples.Microbiology resource announcements · 2019Article
- Unravelling species boundaries in thePersoonia · 2018Article
- Antifungal Susceptibility of the Aspergillus viridinutans Complex: Comparison of TwoAntimicrobial agents and chemotherapy · 2018Article
- Taxonomy and evolution ofComputational and structural biotechnology journal · 2018Review
- Aspergillus fumigatus-Related Species in Clinical Practice.Frontiers in microbiology · 2016Review
- Extrolites of Aspergillus fumigatus and Other Pathogenic Species in Aspergillus Section Fumigati.Frontiers in microbiology · 2015Review
- Genetic relatedness versus biological compatibility between Aspergillus fumigatus and related species.Journal of clinical microbiology · 2014Article
- Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibility.Journal of clinical microbiology · 2013Article
- Aspergillus felis sp. nov., an emerging agent of invasive aspergillosis in humans, cats, and dogs.PloS one · 2013Article
- Phenotypic characteristics of isolates of Aspergillus section Fumigati from different geographic origins and their relationships with genotypic characteristics.BMC infectious diseases · 2011Article
- Re-identification of Aspergillus fumigatus sensu lato based on a new concept of species delimitation.Journal of microbiology (Seoul, Korea) · 2010Article
- Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network.Journal of clinical microbiology · 2009Article
- Chronic invasive aspergillosis caused by Aspergillus viridinutans.Emerging infectious diseases · 2009Article
- Aspergillus section Fumigati typing by PCR-restriction fragment polymorphism.Journal of clinical microbiology · 2009Article
- Multilocus sequence typing of the pathogenic fungus Aspergillus fumigatus.Journal of clinical microbiology · 2007Article
- Aspergillus species identification in the clinical setting.Studies in mycology · 2007Article
- Polyphasic taxonomy of Aspergillus section Fumigati and its teleomorph Neosartorya.Studies in mycology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate whether genetic variants of A. fumigatus are found among clinical isolates, four isolates that were originally identified as poorly sporulating strains of Aspergillus fumigatus were subjected to molecular analysis. DNA sequence analysis of the alkaline protease genes of these isolates showed that each is genetically distinct and each shows substantial variation (7 to 11%) from the A. fumigatus nucleotide sequence. Subsequent morphological examination suggested that all of the isolates could be classified as Aspergillus viridinutans. To clarify the taxonomic status of these four clinical isolates and of two previously identified as atypical A. fumigatus isolates, partial beta-tubulin and 18S rRNA gene sequences were determined. Each of the six atypical strains had a unique beta-tubulin sequence, whereas the sequences of three standard isolates of A. fumigatus, which were included as controls, were identical to the published A. fumigatus beta-tubulin sequence. The very low level of DNA sequence variation detected in standard isolates of A. fumigatus compared with other isolates from members of Aspergillus section Fumigati suggests that it may be a relatively recently evolved species. The 18S rRNA gene of two of the atypical isolates differed from that of A. fumigatus at a single nucleotide position. Phylogenetic analyses do not support the classification of all of these isolates as A. viridinutans. Thus, some of these isolates represent new species which are potential opportunistic pathogens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.