ArticleJournal of clinical microbiology2005
Identification of variable-number tandem-repeat loci in Leptospira interrogans sensu stricto.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 123 citations in OpenAlex.
- A systematic review ofOne health (Amsterdam, Netherlands) · 2026Article
- Comprehensive genotyping and taxonomic analysis uncovers extensive distribution of intermediate Leptospira species in Colombia.World journal of microbiology & biotechnology · 2026Article
- The serological and genetic diversity of theJournal of veterinary research · 2023Article
- A Canine Leptospirosis Clinical Case Due toVeterinary sciences · 2023Article
- Pathogenesis and Genomic Analysis of a Virulent Leptospira Interrogans Serovar Copenhageni Isolated from a Dog with Lethal Infection.Tropical medicine and infectious disease · 2022Article
- Genetic diversity of Leptospira isolates in Lao PDR and genome analysis of an outbreak strain.PLoS neglected tropical diseases · 2021Article
- Molecular epidemiology of Leptospira spp. among wild mammals and a dog in Amami Oshima Island, Japan.PloS one · 2021Article
- Molecular characterization and phylogenetic analysis of human pathogenicPathogens and global health · 2019Article
- Genotyping of Leptospira interrogans isolates from Mexican patients.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019Article
- Genetic diversity of Leptospira interrogans circulating isolates and vaccine strains in China from 1954-2014.Human vaccines & immunotherapeutics · 2019Article
- Genomic Comparison Among Global Isolates ofFrontiers in cellular and infection microbiology · 2018Article
- Molecular typing of Leptospira interrogans serovar Hardjo isolates from leptospirosis outbreaks in Brazilian livestock.BMC veterinary research · 2017Article
- Intrinsic and extrinsic factors related to pathogen infection in wild small mammals in intensive milk cattle and swine production systems.PLoS neglected tropical diseases · 2017Article
- Culture Strategies for Isolation of FastidiousFrontiers in microbiology · 2017Article
- Phenotypic and Molecular Characterization of Leptospira interrogans Isolated from Canis familiaris in Southern Brazil.Current microbiology · 2015Article
- Characterization of Leptospira interrogans Serovars by Polymorphism Variable Number Tandem Repeat Analysis.Jundishapur journal of microbiology · 2015Article
- Isolation of Leptospira interrogans serovar Hardjoprajitno from a calf with clinical leptospirosis in Chile.BMC veterinary research · 2015Article
- Use of a New High Resolution Melting Method for Genotyping Pathogenic Leptospira spp.PloS one · 2015Article
- Leptospira species and serovars identified by MALDI-TOF mass spectrometry after database implementation.BMC research notes · 2014Article
- Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina.Memorias do Instituto Oswaldo Cruz · 2014Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptospira interrogans sensu stricto is responsible for the most frequent and severe cases of human leptospirosis. The epidemiology and clinical features of leptospirosis are usually associated with the serovars and serogroups of Leptospira. Because of the difficulties associated with serological identification of Leptospira strains, we evaluated a novel PCR-based method for typing L. interrogans serovars. Based upon the genome sequence of L. interrogans serovar Lai type strain 5660, 44 loci were analyzed by PCR for their variability in size due to the presence of variable-number tandem repeats (VNTR). Seven VNTR loci were found to be powerful markers for serovar identification, epidemiology, and phylogenetic studies of L. interrogans. This rapid and easy method should greatly contribute to a better knowledge of the epidemiology of Leptospira.
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