ArticleBiophysical journal2005
Coalescence of membrane tethers: experiments, theory, and applications.
Article in Biophysical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed, 204 citations in OpenAlex.
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- Migrasome formation is initiated preferentially in tubular junctions by membrane tension.Biophysical journal · 2025Article
- The Plasma Membrane and Mechanoregulation in Cells.ACS omega · 2024Review
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- Mechano-regulation by clathrin pit-formation and passive cholesterol-dependent tubules during de-adhesion.Cellular and molecular life sciences : CMLS · 2024Article
- Membrane Tubulation with a Biomembrane Force Probe.Membranes · 2023Article
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- Micromechanics of Biomembranes.The Journal of membrane biology · 2022Review
- Quantitative Nanomechanical Analysis of Small Extracellular Vesicles for Tumor Malignancy Indication.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Biomechanics of Neutrophil Tethers.Life (Basel, Switzerland) · 2021Review
- Endocytosis against high turgor pressure is made easier by partial coating and freely rotating base.Biophysical journal · 2021Article
- Influence of membrane-cortex linkers on the extrusion of membrane tubes.Biophysical journal · 2021Article
- Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus.Scientific reports · 2020Article
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- Nonaxisymmetric Shapes of Biological Membranes from Locally Induced Curvature.Biophysical journal · 2020Article
- Mechanical Tension of Biomembranes Can Be Measured by Super Resolution (STED) Microscopy of Force-Induced Nanotubes.Nano letters · 2020Article
- Biological lipid nanotubes and their potential role in evolution.The European physical journal. Special topics · 2020Review
- Mechanical Characterization of Liposomes and Extracellular Vesicles, a Protocol.Frontiers in molecular biosciences · 2020Article
- Glycan-decorated protocells: novel features for rebuilding cellular processes.Interface focus · 2019Review
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tethers are nanocylinders of lipid bilayer membrane, arising in situations ranging from micromanipulation experiments on synthetic vesicles to the formation of dynamic tubular networks in the Golgi apparatus. Relying on the extensive theoretical and experimental works aimed to understand the physics of individual tethers formation, we addressed the problem of the interaction between two nanotubes. By using a combination of micropipette manipulation and optical tweezers, we quantitatively studied the process of coalescence that occurred when the separation distance between both vesicle-tether junctions became smaller than a threshold length. Our experiments, which were supported by an original theoretical analysis, demonstrated that the measurements of the tether force and angle between tethers at coalescence directly yield the bending rigidity, kappa, and the membrane tension, sigma, of the vesicles. Contrary to other methods used to probe the bending rigidity of vesicles, the proposed approach permits a direct measurement of kappa without requiring any control of the membrane tension. Finally, after validation of the method and proposal of possible applications, we experimentally investigated the dynamics of the coalescence process.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.