ReviewThe Journal of physiology2005
Experimental models of developmental programming: consequences of exposure to an energy rich diet during development.
Review in The Journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
123 citing papers in PubMed, 1 synthesis or guideline pooled it, 377 citations in OpenAlex.
- Little appetite for obesity: meta-analysis of the effects of maternal obesogenic diets on offspring food intake and body mass in rodents.International journal of obesity (2005) · 2015Pooled it
- Chromatographic Analyses of SpirulinaMedicina (Kaunas, Lithuania) · 2023Article
- The Effect of Maternal Exposure to a Diet High in Fats and Cholesterol on the Placental Function and Phenotype of the Offspring in a Rabbit Model: A Summary Review of About 15 Years of Research.International journal of molecular sciences · 2023Review
- The social formation of fitness: lifetime consequences of prenatal nutrition and postnatal care in a wild mammal population.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Modification of the serotonergic systems and phenotypes by gestational micronutrients.The Journal of endocrinology · 2023Article
- Nutriepigenomics in Environmental-Associated Oxidative Stress.Antioxidants (Basel, Switzerland) · 2023Review
- The effect of source of protein fed during pregnancy and lactation on the development of characteristics of metabolic syndrome in male offspring of obese Wistar rats.Journal of nutritional science · 2023Article
- Associations Between Maternal Lipid Blood Levels at the 13th Week of Pregnancy and Offspring's Adiposity at Age 11-12 Years.The Journal of clinical endocrinology and metabolism · 2022Article
- Maternal carbohydrate intake during pregnancy is associated with child peripubertal markers of metabolic health but not adiposity.Public health nutrition · 2022Article
- Maternal Protein Restriction Alters the Expression of Proteins Related to the Structure and Functioning of the Rat Offspring Epididymis in an Age-Dependent Manner.Frontiers in cell and developmental biology · 2022Article
- Different Protein Sources in the Maternal Diet of the Rat during Gestation and Lactation Affect Milk Composition and Male Offspring Development during Adulthood.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Using a Microsimulation of Energy Balance to Explore the Influence of Prenatal Sugar-Sweetened Beverage Intake on Child BMI.Obesity (Silver Spring, Md.) · 2021Article
- Omega-6:Omega-3 Fatty Acid Ratio and Total Fat Content of the Maternal Diet Alter Offspring Growth and Fat Deposition in the Rat.Nutrients · 2020Article
- Time-critical influences of gestational diet in a seahorse model of male pregnancy.The Journal of experimental biology · 2020Article
- Risk of hypertension following perinatal adversity: IUGR and prematurity.The Journal of endocrinology · 2019Review
- Effect of maternal obesity on fetal and postnatal baboon (Papio species) early life phenotype.Journal of medical primatology · 2019Article
- High-fat diet in pregnant rats and adverse fetal outcome.Upsala journal of medical sciences · 2019Article
- Maternal high-fat diet reversal improves placental hemodynamics in a nonhuman primate model of diet-induced obesity.International journal of obesity (2005) · 2019Article
- The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats.Physiological reports · 2019Article
- Short-Term Neonatal Oral Administration of Oleanolic Acid Protects against Fructose-Induced Oxidative Stress in the Skeletal Muscles of Suckling Rats.Molecules (Basel, Switzerland) · 2019Article
63 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies in both humans and experimental animals addressing the 'Fetal Origins of Adult Disease' hypothesis have established a relationship between an adverse intrauterine environment and offspring disease in adult life. This phenomenon, termed 'fetal programming' describes a process whereby a stimulus in utero establishes a permanent response in the fetus leading to enhanced susceptibility to later disease. However, the environment, during periods of developmental plasticity in postnatal life, can also 'programme' function. Thus, the terms 'developmental programming' and the 'Developmental Origins of Adult Health and Disease' are preferentially utilized. The 'Thrifty Phenotype' hypothesis explained the association between insufficient in utero nutrition and the later development of Type 2 diabetes. Most recently the 'Predictive Adaptive Response' hypothesis proposes that the degree of mismatch between the pre- and postnatal environments is an important determinant of subsequent disease. Epidemiological studies have indicated that fetal growth restriction correlates with later disease, implying that fetal nutritional deprivation is a strong programming stimulus. This prompted the development of experimental animal models using controlled maternal calorie, protein or macronutrient deficiency during key periods of gestation. However, in many societies, maternal and postnatal nutrition are either sufficient or excessive. Here, we examine findings from a range of nutritional studies examining maternal and/or postnatal nutritional excess. There is supportive evidence from a limited number of studies to test the 'Predictive Adaptive Response' hypothesis. These suggest that maternal over-nutrition is deleterious to the health of offspring and can result in a phenotype of the offspring that is characteristic of metabolic syndrome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.