Evidence map›Paper›PMID 15691976›Full record

ArticleApplied and environmental microbiology2005

High-level acetaldehyde production in Lactococcus lactis by metabolic engineering.

Roger S Bongers, Marcel H N Hoefnagel, Michiel Kleerebezem

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Fermentation Characteristics of Fermented Milk withMolecules (Basel, Switzerland) · 2024
    Article
  3. Enzymatic reactions towards aldehydes: An overview.Flavour and fragrance journal · 2023
    Review
  4. Yeast-based production and in situ purification of acetaldehyde.Bioprocess and biosystems engineering · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Development ofFrontiers in microbiology · 2020
    Article
  9. Article
  10. Review
  11. Review
  12. Improvement of Acetaldehyde Production inFrontiers in microbiology · 2019
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Roger S BongersNIZO food research, Department of Flavour and Natural Ingredients, P.O. Box 20, 6710 BA Ede, The Netherlands. Roger.Bongers@nizo.nl
Marcel H N Hoefnagel
Michiel Kleerebezem
Nederlands Instituut Voor Zuivel Oonderzoek · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient conversion of glucose to acetaldehyde is achieved by nisin-controlled overexpression of Zymomonas mobilis pyruvate decarboxylase (pdc) and Lactococcus lactis NADH oxidase (nox) in L. lactis. In resting cells, almost 50% of the glucose consumed could be redirected towards acetaldehyde by combined overexpression of pdc and nox under anaerobic conditions.

Indexed as

Gene Expression Regulation, BacterialAcetaldehydeAnaerobiosisCulture MediaGenetic EngineeringLactococcus lactisMultienzyme ComplexesNADH, NADPH OxidoreductasesPyruvate DecarboxylaseZymomonasAcetaldehydeCulture MediaMultienzyme ComplexesNADH, NADPH OxidoreductasesNADH oxidasePyruvate Decarboxylase

Identifiers

PMID15691976
PMCPMC546684
OpenAlexW2120054826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.