Evidence map›Paper›PMID 15691622›Full record

Trial reportAmerican journal of hypertension2005

A randomized controlled trial of stress reduction in African Americans treated for hypertension for over one year.

Robert H Schneider, Charles N Alexander, Frank Staggers, David W Orme-Johnson, Maxwell Rainforth, John W Salerno, William Sheppard, Amparo Castillo-Richmond, Vernon A Barnes, Sanford I Nidich

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of hypertension, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00000537 (Stress Reduction & CVD Morbidity and Mortality in Blacks), which is not on this map. Cited by 49 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 8 pooled it
8.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00000537 phase2completednot on this map

Stress Reduction & CVD Morbidity and Mortality in Blacks

TypeinterventionalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran1992 to 2008ConditionsCardiovascular Diseases, Heart Diseases, Hypertension, Vascular DiseasesArmsmeditation, relaxation
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 8 syntheses or guidelines pooled it, 193 citations in OpenAlex.

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  4. Systematic Review for the Medical Applications of Meditation in Randomized Controlled Trials.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Robert H SchneiderInstitute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, Iowa, USA. rschneider@mum.edu
Charles N Alexander
Frank Staggers
David W Orme-Johnson
Maxwell Rainforth
John W Salerno
William Sheppard
Amparo Castillo-Richmond
Vernon A Barnes
Sanford I Nidich
Maharishi International University · USWest Health · USAugusta University · USOASIS Clinic · USUniversity of Illinois Chicago · US

Funding

Effects of Herbal Antioxidants on CVD in Older BlacksP50AT000082 · NCCIH · MAHARISHI UNIVERSITY OF MANAGEMENT · PI SCHNEIDER, ROBERT · 1999 to 2004
$6.2M
STRESS REDUCTION IN ELDERLY BLACKS WITH HYPERTENSIONR01HL048107 · NHLBI · MAHARISHI UNIVERSITY OF MANAGEMENT · PI SCHNEIDER, ROBERT · 1992 to 2006
$2.3M
NCCIH NIH HHS 1P50AT00082NCCIH NIH HHS P50 AT000082NHLBI NIH HHS 1 R01 HL48107NHLBI NIH HHS R01 HL048107
6 · The paper itself

Abstract

backgroundPsychosocial stress has been implicated in the disproportionately higher rates of hypertension among African Americans. This randomized controlled trial compared the effects of two stress reduction techniques and a health education control program on hypertension during a period of 1 year in African-American men and women (N = 150, mean age 49 +/- 10 years, mean blood pressure (BP) = 142/95 mm Hg) at an urban community health center.

methodsInterventions included 20 min twice a day of Transcendental Meditation (TM) or progressive muscle relaxation (PMR), or participation in conventional health education (HE) classes. All subjects continued usual medical care. Outcomes assessed were systolic BP and diastolic BP at 3, 6, 9, and 12 months after treatment, analyzed by repeated measures ANCOVA.

resultsThe TM group showed decreases in systolic BP/diastolic BP of -3.1/-5.7 mm Hg compared to -0.5/-2.9 mm Hg for PMR or HE, (P = .12 to .17 for systolic BP, P = .01 for diastolic BP). In addition the TM group demonstrated reduced use of antihypertensive medication relative to increases for PMR (P = .001) and HE (P = .09) groups. Group analysis by gender showed that women practicing TM had decreased BP (-7.3/-6.9 mm Hg) significantly more than women practicing PMR (0.7/-2.7 mm Hg) or HE (-.07/-3.0 mm Hg) (P .01 to .03). The change in men praticing TM (0.2 /-4.7 mm Hg) was greater than men practicing HE (-0.9/-2.0 mm Hg) for diastolic BP only (P = .09,) and not different from PMR men (-2.0/-3.1).

conclusionsA selected stress reduction approach, the Transcendental Meditation program, may be useful as an adjunct in the long-term treatment of hypertension in African Americans.

Indexed as

MeditationPatient Education as TopicAdultAntihypertensive AgentsBlack or African AmericanBlood PressureCaliforniaFemaleFollow-Up StudiesHumansHypertensionLife StyleMaleMiddle AgedPatient ComplianceSex FactorsAntihypertensive Agents

Identifiers

PMID15691622
PMCPMC2224896
OpenAlexW1988193867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.